Results 161 to 170 of about 17,822,863 (260)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Artificial Intelligence Use Among Health Care Professionals in the United States and United Kingdom: Cross-National Survey. [PDF]

JMIR Form Res
Sezgin E, Lee J, Jadczyk T, Taxter AJ.
europepmc   +1 more source

The role of patents in the transfer of technology to developing countries.

95p
Role
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Offensive unpredictability and defensive tracking in intergroup conflict show sex-differentiated patterns. [PDF]

iScience
Zhang H, Zhang C, Widjaja A, Ma Y.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Clear Positive MOG Antibodies in Adults With Multiple Sclerosis Features: Diagnostic Challenges. [PDF]

Neurol Neuroimmunol Neuroinflamm
Garcia J, Shor N, Boutiere C, Pique J, Boudot De La Motte M, Guillaume M, Delourme A, Zephir H, Ciron J, Carra-Dalliere C, Buissonnière P, Mélé N, Aboab J, Cohen M, Wang A, Couturier J, Rusu D, Thouvenot E, Laplaud DA, Ruet A, Bourre B, Durand-Dubief F, Benyahya L, Collongues N, Michel L, Deschamps R, Papeix C, Audoin B, Stankoff B, Touitou V, Vignal Clermont C, Sterlin D, Marignier R, Maillart E, NOMADMUS study group.   +34 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Intention-to-Leave Among New Zealand Podiatrists: A Cross-Sectional Survey of Frequency and Associated Factors. [PDF]

J Foot Ankle Res
Clarke M, Frecklington M, Zeng I, Carroll MR, Siegert RJ, Stewart S.   +5 more
europepmc   +1 more source