Results 141 to 150 of about 18,453,462 (297)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Tobacco use among adolescent students and the influence of role models
Indian Journal of Community Medicine, 2010 Background: Seventy per cent of premature deaths among adults are due to behavioral patterns that emerge in adolescence, including smoking. Objective: The objective was to study the prevalence of tobacco use among adolescent students in South Delhi and ...
Sharma Rahul +2 more
doaj
Agency and role models: do they matter for adolescent girls' sexual and reproductive health? [PDF]
BMC Womens Health, 2023 Ogunbiyi BO +3 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
'A role model is like a mosaic': reimagining URiM students' role models in medical school. [PDF]
BMC Med Educ, 2023 Spaans I +3 more
europepmc +1 more source