Results 181 to 190 of about 18,453,462 (297)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Center for Teaching Old Models New Tricks (TOMNET): Data Management Plan (DMP)

open access: yes
This document constitutes a Data Management Plan (DMP) for the Center for Teaching Old Models New Tricks (TOMNET), a US Department of Transportation Tier 1 University Transportation Center (UTC) led by Arizona State University (ASU).
Center for Teaching Old Models New Tricks (TOMNET)
core  

Leading by example: how to empower supervisors as role models. [PDF]

open access: yesFront Res Metr Anal
van Loon M   +3 more
europepmc   +1 more source

The Impact of Role Models, Mentors, and Heroes on Academic and Social Outcomes in Adolescents. [PDF]

open access: yesCureus, 2022
Atif H   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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