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Correction for Mehmood et al., Teacher vaccinations enhance student achievement in Pakistan: The role of role models and theory of mind. [PDF]
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
LET'S PUT OUR CHILDREN ABOVE FRAY PROGRAM ADDRESSES NEEDS OF INNER-CITY BLACK YOUTH
PERRYMAN W # ROLE MODELS LTD; TIMES
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IEEE Software, 1999
In building an object-oriented system, we can characterize an object's dynamic nature by modeling its roles. But some modeling abstractions represent roles without addressing the relationships among them. The Cascade pattern, which represents layered and ordered whole-part relationships between objects, solves this problem. The author's examples from a
Liping Zhao 0001, Ted Foster
openaire +3 more sources
In building an object-oriented system, we can characterize an object's dynamic nature by modeling its roles. But some modeling abstractions represent roles without addressing the relationships among them. The Cascade pattern, which represents layered and ordered whole-part relationships between objects, solves this problem. The author's examples from a
Liping Zhao 0001, Ted Foster
openaire +3 more sources

