Results 121 to 130 of about 441,946 (258)

Using a virtual reality role-playing game to enhance interaction dynamics and improve social attitudes toward transgender people. [PDF]

Sci Rep
Crone CL, Kallen RW, Richardson MJ.
europepmc   +1 more source

Social skills training with a tabletop role-playing game, before and during the pandemic of 2020: in-person and online group sessions. [PDF]

Front Psychiatry, 2023
Henning G, de Oliveira RR, de Andrade MTP, Gallo RV, Benevides RR, Gomes RAF, Fukue LEK, Lima AV, de Oliveira MBBZN, de Oliveira DAM, Werpp M, Moraes L, Neto FL.   +12 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Effectiveness of Peer Education, Mentorship and Role-Playing Approaches in Developing Clinical Skills Among Iranian Nursing Students: A Systematic Review. [PDF]

Health Sci Rep
Ghonchehpour A, Alipoor M, Farmitani Z, Ghorbani F, Nouhi E.   +4 more
europepmc   +1 more source

Evaluating the Feasibility of a Multiplayer Role-Playing Game as a Behavioral Health Intervention in Adolescent Patients With Chronic Physical or Mental Conditions: Protocol for a Cohort Study. [PDF]

JMIR Res Protoc, 2023
Babichenko D, Radovic A, Patel R, Hester A, Powell K, Eggers N, Happe D.   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The efficacy of virtual reality flipped learning with collaborative role-playing in nursing education. [PDF]

BMC Nurs
Li Y, Wu JG, Zhang D, Chen Y.
europepmc   +1 more source

Sex Differences in Competitiveness in Massively Multiplayer Online Role-Playing Games (MMORPGs). [PDF]

Evol Psychol, 2022
Deaner RO, Dunlap LC, Bleske-Rechek A.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Enhancing dental students' motivation and legal knowledge via courtroom role-playing. [PDF]

BMC Med Educ
Hsu WC, Hung YN, Chen HH, Fuh LJ, Liao SC.   +4 more
europepmc   +1 more source