Results 71 to 80 of about 22,489 (214)

Keefektifan metode role playing terhadap keaktifan dan kerja sama siswa dalam pembelajaran IPS

open access: yesHarmoni Sosial: Jurnal Pendidikan IPS, 2018
Penelitian ini bertujuan untuk mengungkapkan keefektifan metode role playing dibandingkan dengan metode ceramah dalam peningkatan: (a) keaktifan siswa dan (b) kerja sama siswa dalam pembelajaran IPS kelas VIII di SMP Negeri 1 Marioriawa.
Risva Anggriani, Ishartiwi Ishartiwi
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Keefektifan Layanan Bimbingan Kelompok Melalui Teknik Role Playing untuk Mengurangi Perilaku Bulliying

open access: yesEdukasia, 2023
The existence of bullying behavior in schools is certainly a scourge for educational units. With this research, namely applying the role playing method to class VII students at TanjungBalai 4 Public Middle School for the 2023-2024 academic year, this ...
Stariah, Ahmad Syarqawi
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From “Playing a Role” to “Role-Playing Games”: The Genealogy and History of the Term “Role-Playing”

open access: yesInternational Journal of Role-Playing
This article presents a comprehensive semantic genealogy of the term “role-playing,” tracing its multifaceted evolution from theatrical origins to its current association with leisure activities, especially role-playing games (RPGs). Rather than offering yet another contested definition, it maps the shifting meanings of “role-playing” across nine ...
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy