Results 31 to 40 of about 6,905,317 (309)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Civil society roles in transition: towards sustainable food? [PDF]

open access: yes, 2014
Civil society organisations (CSOs) are often conspicuously absent in policy discussions and strategic planning about food security and the environmental sustainability of food systems.
Durrant, Rachael
core   +1 more source

Native American Educators and Their Leadership Roles on Reservations in the Northern Great Plains

open access: yes, 2016
Native American educators occupy a significant place within their respective communities. In this article I report findings from a qualitative investigation on the various ways Native educators define their roles to their students, schools, and ...
Huffman, Terry
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Some Epistemic Roles for Curiosity [PDF]

open access: yes, 2018
I start with a critical discussion of some attempts to ground epistemic normativity in curiosity. Then I develop three positive proposals. The first of these proposals is more or less purely philosophical; the second two reside at the interdisciplinary ...
Whitcomb, Dennis
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Changing Roles of Library Professionals [PDF]

open access: yes, 2000
Includes bibliographical references (p.
Simmons-Welburn, Janice
core   +2 more sources

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Bioethics in the Public and Policy Spaces: Lessons from the Covid Years

open access: yesCanadian Journal of Bioethics
The Covid-19 pandemic presented numerous ethical challenges, highlighting the critical role of bioethicists in public spaces and policymaking. Bioethicists acted as guardians against systemic injustices, critics of health policy decisions, and ...
Bryn Williams-Jones, Sihem Neila Abtroun
doaj   +1 more source

Central Public Administration Authority at the Regional Level in Albania

open access: yesStudia Iuridica Lublinensia, 2022
The Albanian regional governance system is based on both decentralization and deconcentration, each of them aiming at bringing services close to the public. To make the multilevel governance system work, the prefect is a keystone of public administration
Nevila Xhindi, Noémia Bessa Vilela
doaj   +1 more source

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