USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian +9 more
wiley +1 more source
Tailoring the Surface Integrity of Ti-6Al-4V Alloy by Ultrasonic Surface Rolling Process: A Review. [PDF]
Li G +5 more
europepmc +1 more source
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu +12 more
wiley +1 more source
Mechanical Properties and Corrosion Behavior of Biodegradable Metals: Current Challenges. [PDF]
Nazeran F +5 more
europepmc +1 more source
This study established a one‐step method inducing pro‐spermatogonia‐like (activating SOX17) and oogonia‐like (activating SOX17/TFAP2C) cells from porcine pgEpiSCs with a NANOS3‐tdTomato reporter. EGF activates the core PGC program and supports survival; BMP4 further induces NANOS3 and DDX4 expression; IWR1 enhances PGCLC efficiency by suppressing ...
Pengcheng He +14 more
wiley +1 more source
MGFR-ViT: A Multi-Scale Gated Feature Refinement Vision Transformer for Vibration-Based Fault Diagnosis. [PDF]
Yan Y +6 more
europepmc +1 more source
Composite‐based flexible electronics integrate biodegradable polymers, conductive networks, and multilayer device architectures to balance electrical performance, mechanical durability, and controlled degradation. Interfacial engineering and encapsulation regulate transport stability and operational lifetime, while programmed disassembly enables ...
Sayam, Sangho Cho
wiley +1 more source
CNN Bearing Fault Diagnosis Based on Symmetric Point Pattern Feature Fusion with Multi-Source Resonance Sparse Components. [PDF]
Liu Y +7 more
europepmc +1 more source
Physics-guided cross-domain adaptation: a hierarchical hybrid transformer framework with contrastive learning for robust fault diagnosis under variable working conditions. [PDF]
Liu L, Hao C, Xiong L, Lv X.
europepmc +1 more source
An End-to-End Fault Diagnosis Model for Rolling Bearings Based on Multi-Scale Convolution and the Kolmogorov-Arnold Network. [PDF]
Yu D, Wang Z, Liu J, Liu H, Ying C.
europepmc +1 more source

