Results 21 to 30 of about 84,074 (260)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Uma embaixada portuguesa do final da Idade Média: de Lisboa a Roma, 1443-1445
Anuario de Estudios Medievales, 2018 Este artigo analisa uma embaixada enviada pelo regente de Portugal a Roma entre 1443 e 1445. Os objetivos, os resultados, o perfil do embaixador, as viagens e as finanças são os aspetos privilegiados.
Diogo Faria
doaj +1 more source
Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas +39 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia, 2016 Research literature shows that Roma children’s literacy skills are less developed compared with their non-Roma peers. This situation represents a major deterrent in integration of Roma within the majority of countries of European Union. In this study we
Dacian Dorin DOLEAN +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
RUDN Journal of Public AdministrationThe study provides an analysis of the Russian system of state governance of national policy, using the example of the Roma population, who are indigenous to Russia.
Anna Yu. Anfimova
doaj +1 more source
Roma Cumhuriyet Dönemi’nde Exilium (Sürgün)
Selçuk Üniversitesi Edebiyat Fakültesi Dergisi, 2021 Roma hukukunda exilium, yani sürgün cumhuriyetin ilk dönemlerinde yazılı bir yasaya dayanarak uygulanmamıştır. Bununla birlikte sürgün, sanığın işlediği iddia edilen suça göre gönüllü veya zorunlu sürgün olarak uygulanmıştır.
Ümran Ozan Karahan
doaj +1 more source