Results 21 to 30 of about 86,163 (263)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Uma embaixada portuguesa do final da Idade Média: de Lisboa a Roma, 1443-1445

Anuario de Estudios Medievales, 2018
Este artigo analisa uma embaixada enviada pelo regente de Portugal a Roma entre 1443 e 1445. Os objetivos, os resultados, o perfil do embaixador, as viagens e as finanças são os aspetos privilegiados.
Diogo Faria
doaj   +1 more source

Roma families and teachers: gaining visibility and recognition through the implementation of socio-educational policies

Educazione Interculturale, 2023
One of the central issues of our age is early school leaving. In this paper it was decided to analyze to what extent early school leaving involves the Roma, one of the most marginalized social groups.
Silvia Carbone
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

WHAT FACTORS INFLUENCE THE DEVELOPMENT OF READING FLUENCY OF ROMA CHILDREN? THE EFFECTS OF WHOLE-CLASS REPEATED READINGS AND SCHOOL ABSENTEEISM

Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia, 2016
Research literature shows that Roma children’s literacy skills are less developed compared with their non-Roma peers. This situation represents a major deterrent in integration of Roma within the majority of countries of European Union. In this study we
Dacian Dorin DOLEAN, Ioana TINCAS, Crina DAMSA   +2 more
doaj  

Analysis of Interventions to Reduce Antigypsyism in Slovakia: A Social Psychology Perspective

Slovenský Národopis, 2021
Despite numerous efforts of Roma inclusion from various State and non-governmental organisations, segregation and socioeconomic marginalisation of the Roma is still widespread in Slovakia.
Hargašová Lucia, Lášticová Barbara, Poslon Xenia Daniela, Belán Dóra   +3 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

The experience of implementing Soviet policies of assimilation of national minorities: application in contemporary public administration

RUDN Journal of Public Administration
The study provides an analysis of the Russian system of state governance of national policy, using the example of the Roma population, who are indigenous to Russia.
Anna Yu. Anfimova
doaj   +1 more source