Results 121 to 130 of about 686,099 (268)

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, Volume 183, Issue 10, Page 2256-2272, May 2026.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Engineered Production of Hydroxycinnamoyl Tyramine Conjugates Limits the Growth of the Pathogen Pseudomonas syringae in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 5, Page 2516-2530, May 2026.
ABSTRACT Hydroxycinnamoyl tyramine conjugates are phenolamides produced by plants in response to pathogen attack and biotic stresses. Their proposed mechanisms of action include cytotoxicity towards pathogens, cell wall reinforcement to restrict pathogen proliferation, and signaling activity to trigger general stress responses.
Halbay Turumtay, Jana A. Hassan, Sami Kazaz, Yu Gao, Yang Tian, Yi‐Chun Chen, Ramu Kakumanu, Emine Akyuz Turumtay, Mehmet Veysi Cetiz, Hemant Choudhary, Edward E. K. Baidoo, Blake A. Simmons, Henrik V. Scheller, Jennifer D. Lewis, Aymerick Eudes   +14 more
wiley   +1 more source

Marina El-Alamein Polish-Egyptian conservation mission : research and conservation in the 2011 season [PDF]

, 2014
In 2011, the program of the Polish-Egyptian Conservation Mission to Marina el-Alamein included research and conservation in the public quarter of the ancient town, at the necropolis and in a few houses.
Bąkowska-Czerner, Grażyna, Czerner, Rafał, Grzegorek, Wiesław, Jasiewicz, Agata   +3 more
core  

Horace and Statius at Tibur: an Interpretation of Silvae 1.3 [PDF]

, 1988
published or submitted for ...
Newlands, Carole E.
core  

Inscripción Romana Aparecida en Armuña del Almanzora (Almería)

Zephyrus, 2009
RESUMEN: Este artículo recoge una nueva inscripción romana aparecida en Armuña del Almanzora (Almería) de gran interés para el conocimiento de algunos aspectos socioeconómicos de la Hispânia Antiqua.
Pedro RESINA SOLA, Mauricio PASTOR MUÑOZ   +1 more
doaj  

Generator of Hypotheses for a Digital Restitution of Built Heritage: Case of Roman Imperial Baths of North Africa [PDF]

, 2014
In this paper, we present an approach for developing a tool for the restitution of built heritage and we take as a case study the Roman imperial baths of North Africa.
Houda, Lichiheb, Mounir, Dhouib
core   +1 more source

Laying hens in furnished cages [PDF]

, 2003
Concern for the welfare of laying hens housed in conventional cages has led to a change of the Animal Welfare Legislation in Sweden, implying that cages must provide possibilities for hens to lay eggs in a nest, to rest on a perch and to use litter. Such
Wall, Helena
core  

An environmental and cultural study at Lake Maryut, Lower Egypt: a research prospectus [PDF]

, 1980
African Studies Center Working Paper No ...
Gabel, Creighton, Petruso, Karl
core  

Contributions to the knowledge of the geohydraulic model and geothermal potential of the São Vicente Medical Spa aquifer system (Central Portugal)

Discover Water
São Vicente Medical Spa is located in mainland Portugal (Southwest Europe) and has been using thermal waters for therapeutic purposes for a long time. The Romans were known to have used its sulphureous waters around 2000 years ago.
L. M. Ferreira-Gomes, J. F. Santos-Alves
doaj   +1 more source