Results 131 to 140 of about 9,212 (287)

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li   +7 more
wiley   +1 more source

Policy Spandrels: How Design Decisions Can Open Up Spaces for Unintended Policy Change

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT This article introduces the concept of policy spandrels to make sense of public policies producing second‐order effects that are unintentional from the perspective of policy design and yet are fraught with consequences. By analogy with architectural spandrels—leftover spaces that can be used for unforeseen purposes—policy change can be enabled
Martino Maggetti
wiley   +1 more source

The Role of Digital Twin Technology in Enhancing Energy Efficiency in Buildings: A Systematic Literature Review

open access: yesEnergy Science &Engineering, EarlyView.
Digital Twin (DT) technology enhances building energy efficiency by enabling continuous monitoring, predictive maintenance, and operational optimization within Building Energy Management Systems. Through real‐time data integration and simulation, DTs provide dynamic feedback loops that optimize performance, reduce operational costs, and improve ...
Suqi Wang   +6 more
wiley   +1 more source

Char Layer Thickness Evolution During Structural Timber Fire Experiment and Final Density Profile

open access: yesFire and Materials, EarlyView.
ABSTRACT This paper evaluates several non‐destructive experimental methods for determining the char layer thickness and its density profile in structural timber samples exposed to standard ISO 834 fire curve experiments. Microwave echo pulse, ultrasonic echo pulse, X‐ray computed tomography, and resistance drilling were evaluated.
Fernando Pérez Pérez   +4 more
wiley   +1 more source

Finalisation of the European Approach to Assess the Fire Performance of Facades—Brief Information on the Outcome of the Project

open access: yesFire and Materials, EarlyView.
ABSTRACT This research was conducted within the framework of project SI2.825082, funded by the European Commission—DG GROW. The project's objective was to finalise a European approach for assessing the fire performance of façades under medium and large fire exposure conditions.
Péter Tóth   +7 more
wiley   +1 more source

Hydrogen Halide Gas Sensors: Active Materials, Operation Principles, and Emerging Technologies

open access: yesInterdisciplinary Materials, EarlyView.
This review considers hydrogen halide (HX) gas sensors across functional materials and principles: acoustic, chemical, optical and nanophotonic. The strong acidity and reactivity of HX gases are discussed as constraints for stability and selectivity of these devices.
Xiuzhen Liu   +12 more
wiley   +1 more source

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