Results 41 to 50 of about 624,561 (343)

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

Information Access in a Multilingual World: Transitioning from Research to Real-World Applications [PDF]

open access: yes, 2009
Multilingual Information Access (MLIA) is at a turning point wherein substantial real-world applications are being introduced after fifteen years of research into cross-language information retrieval, question answering, statistical machine translation ...
Gey, Fredric   +2 more
core   +2 more sources

Hydration Behavior of Tricalcium Silicate in Seawater Relevant Salt Systems: A Hybrid Study with the Aid of Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
The hydration behavior of C3S in seawater‐relevant solutions is studied based on experiments, boundary nucleation and growth (BNG) modeling, and machine learning. The main ions included in seawater modify hydration mechanisms, with MgCl2 showing the strongest acceleration effect at the same concentration.
Yanjie Sun   +6 more
wiley   +1 more source

Hispellum: A case study of the Augustan agenda [PDF]

open access: yes, 2015
A survey of archaeological, epigraphic, and literary sources demonstrates that Hispellum is an adequate case study to examine the different stages through which Augustus’ Romanization program was implemented.
Carboni, Tiziana
core   +1 more source

Vascular Abnormalities in Hypermobile Ehlers–Danlos Syndrome: A Retrospective Cohort Study

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypermobile Ehlers–Danlos syndrome (hEDS), while generally free from severe vascular complications, may occasionally present with cardiac and vascular abnormalities that warrant specific investigation. While studies have been conducted on the prevalence of cardiac involvement, none have focused on vascular aspects. This retrospective study was
Thomas Gehin   +4 more
wiley   +1 more source

Wokół latynizacji hebrajskiego na łamach „Mecudy” – język narodowy między Orientem a Okcydentem

open access: yesStudia Judaica
The aim of the article was to examine the discourse on the romanization (latinization) of Hebrew in the Betar magazine Mecuda, published in 1935– 1938 in Warsaw, London, and Paris by Ajzik Remba (1907–
Maciej Ratajczyk
doaj   +1 more source

Romanization south-western Scotland [PDF]

open access: yes, 1966
Not ...
Wilson, Allan
core  

KARA KİTAP: ROMAN İÇİNDE ROMAN İÇİNDE ROMAN...

open access: yesKesit Akademi, 2015
In this study, the usage of "mise en abyme", a technique of metafiction, which means "falling into eternity" in French and translated as early narration, in Orhan Pamuk's novel named "Black Book" is going to be analysed. Mise en abyme is a metafictional technique, New Novalists who lay the foundation of post modern novel by rising against the novel of
openaire   +2 more sources

Family Dispute Resolution in Australia: The Under‐Servicing of Indigenous, Migrant and Refugee Families Experiencing Family Violence

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Improving access to legal services for Indigenous, migrant and refugee women is critical to addressing family violence. In this context, Family Dispute Resolution (FDR) has long been discussed as a solution for separating families. This paper presents key findings of a research evaluation of an Australian Government $8.37 million pilot project
Siobhan McDonnell, Alyson Wright
wiley   +1 more source

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