Results 181 to 190 of about 186,570 (314)

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

British Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Correction: Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network. [PDF]

Front Immunol
Giordano C, Gentile D, Straface E, Gallo R, Cristiani CM, Abatino A, Pastore A, Celano M, Arcucci A, Albano F, Falco G, Veneziano C, Santamaria G, Aversa I, Isdraele Romano L, Palmieri C, Fiume G.   +16 more
europepmc   +1 more source

Prevalence, conceptual distinctiveness, and cross‐sectional correlates of climate worry in Canadian adolescents

Child and Adolescent Mental Health, EarlyView.
Background As the impacts of the climate crisis escalate, adolescents face increasing threats to their health and well‐being. However, little is known about the extent to which young adolescents experience climate worry (both in its general affective response and its specific cognitive concerns) and whether it is distinguishable from generalized ...
Joanne L. Park, Audrey‐Ann Deneault, Brae Anne McArthur, Suzanne Tough, Sheri Madigan   +4 more
wiley   +1 more source

Correction: In Vivo Evaluation of SING IMT™ Alignment for Late-Stage Age-Related Macular Degeneration Using Anterior Segment OCT. [PDF]

Ophthalmol Ther
de Angelis L, Galasso M, Di Simplicio S, Raimondi R, Vidal-Aroca F, Romano MR, Toro MD, Rizzo S, Barca F.   +8 more
europepmc   +1 more source

A Randomised Controlled Trial Comparing a One‐Piece Zirconia Tissue‐Level Implant and Two‐Piece Titanium Bone‐Level Implant for Maxillary Single Tooth Replacement—3 year Results

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This RCT evaluated and compared the clinical performance of zirconia and titanium dental implants placed in the maxillary premolar region. Outcomes were assessed 3 years after prosthetic loading and included marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs ...
J. H. W. de Beus, M. S. Cune, L. Muijselaar, J. W. A. Slot, C. Jensen‐Louwerse, S. la Bastide‐van Gemert, H. J. A. Meijer, G. M. Raghoebar, U. Schepke   +8 more
wiley   +1 more source

C AN AQUEOUS PROTEOMICS PREDICT THE RECURRENCE OF RHEGMATOGENOUS RETINAL DETACHMENT? [PDF]

Retina
Zingale GA, Giammaria S, Pandino I, Placentino L, Ripandelli G, Grasso G, Steel DH, Romano MR, Sbardella D, Rossi T.   +9 more
europepmc   +1 more source

Estimating the total mortality of seabirds following a marine heat wave

Conservation Biology, EarlyView.
Abstract Marine heat waves detrimentally affect a range of marine species, including seabirds, and are increasing in frequency and severity. When thousands of dead seabirds wash up on beaches, the public becomes concerned. However, the number of dead birds recorded on beaches is only a fraction of the total mortality; most birds perish at sea.
Jennifer L. Lavers, William Fulton, Silke Stuckenbrock, Alexander L. Bond   +3 more
wiley   +1 more source

Estimation of the Knee Joint with Single-Camera Smartphone. [PDF]

Sensors (Basel)
Russo M, Ricciardi C, Romano M, Santoriello V, Ponsiglione AM, Amato F, Spadea MF.   +6 more
europepmc   +1 more source

Monitoring wildlife health for diseases with visible signs by integrating camera traps with marked individuals

Conservation Biology, EarlyView.
Abstract Monitoring wildlife health is essential for conservation and management, wildlife and livestock welfare, and public health in a One Health framework. Yet, wildlife health monitoring often requires long‐term fieldwork and intensive sampling, which can be costly or logistically challenging, especially for remote, rare, or elusive populations. To
Jonathan Tichon, Roi Lapid, Roni King, Elyasaf Freiman, Orr Spiegel, Erez Baruchi, Aviam Atar, Shirli Bar‐David, David Saltz   +8 more
wiley   +1 more source

A Case Study and Review of the Literature on IgA Nephropathy in Crohn's Disease. [PDF]

Clin Case Rep
Vazzana GF, Romano A, Casuscelli C, La Spada A, Santoro D, Chimenz R, Romano C.   +6 more
europepmc   +1 more source