Results 191 to 200 of about 1,461,446 (283)

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Consensus statement on mesotherapy for clinical and regulatory practice. [PDF]

Rheumatol Int
Mammucari M, Russo D, Maggiori E, Di Marzo R, Rossi M, Lugli M, Migliore A, Leone R, Koszela K, Bertinato L, Aloi TL, Bini F, Brugin E, Beltrami G, Scorcu M, Corrado B, Catizzone A, Cirfera V, Rocchi P, Colonna M, De Vito A, Finco G, Gori F, Marotto D, Natoli S, Sideli C, Varano M, Zurlo V, Anedda C, Antonaccio P, Antonelli A, Morselli FA, Beatini A, Bissi F, Boito B, Bruni M, Cacciatore F, Capeti L, Carusone A, Celani F, Coccetti B, Conte F, Cosmai D, Costumato A, Cremasco F, Crescenzo R, Cresta P, Dalmonte S, Gentile R, Ladiana N, Laurenza M, Presti CL, Lagreca N, Licheri AM, Marcolongo SP, Marcuccio F, Mascolo M, Mauriello V, Moccia E, Moretti CT, Muzi F, Notarrigo P, Perletto F, Pini A, Pistolesi E, Piombino L, Polistina C, Rana N, Ramponi V, Raso S, Rodofili C, Schirò P, Servili A, Somaschi M, Taccagna DM, Tomasell F, Tufaro G, Tumminelli L, Viglione G, Violo B, Vitali E, Antonaci L, Bertoni L, Baioccato V, Bifarini B, Carpenedo R, Chinè E, Ceniti S, Dorato D, Ferrari F, Fiorentini AG, Gallo A, Gallo R, Chiara G, Costanza G, Palermi S, Paolucci T, Preite U, Santini S, Savina MA, Scanu MP, Trocchi G, Troili F, Vecchiato M, Amore LA, Ciccotti RM, Tuzi A, Alama E, Canarecci S, Severoni S, Sozio MP, Varrassi G.   +111 more
europepmc   +1 more source

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer, Mauro Contini, Michele Emdin, Damiano Magrì, Alice Bonomi, Elisabetta Salvioni, Fabrizio Celeste, Alberico Del Torto, Claudio Passino, Christophe D.J. Capelle, Chiara Arzilli, Emiliano Fiori, Nicolò Capra, Christina Kronberger, Nikita Ermolaev, Andreas Kammerlander, Beatrice Musumeci, Giuseppe Vergaro, Vincenzo Castiglione, René Rettl, Giacomo Tini, Andrea Baggiano, Iacopo Fabiani, Susanna Sciomer, Roza Badr Eslam, Piergiuseppe Agostoni   +25 more
wiley   +1 more source

Case Report: Extracorporeal photopheresis for cutaneous lupus erythematosus induces putatively atheroprotective B and T cell responses. [PDF]

Front Immunol
Visentini M, Ozsvar-Kozma M, Pacella I, Pinzon Grimaldos A, Falco F, Shafii-Bafti M, Minicocci I, La Gualana F, Carlesimo M, Casato M, Basili S, Arca M, Piconese S, Fiorilli M, Binder CJ.   +14 more
europepmc   +1 more source

Policy Spandrels: How Design Decisions Can Open Up Spaces for Unintended Policy Change

European Policy Analysis, EarlyView.
ABSTRACT This article introduces the concept of policy spandrels to make sense of public policies producing second‐order effects that are unintentional from the perspective of policy design and yet are fraught with consequences. By analogy with architectural spandrels—leftover spaces that can be used for unforeseen purposes—policy change can be enabled
Martino Maggetti
wiley   +1 more source

Oxidative Stress and Endothelial Dysfunction in Patients with Hypertensive Nephropathy: Role of the Mediterranean Diet. [PDF]

Int J Mol Sci
Salomone L, Menichelli D, Azzara I, Damosso PM, Cammisotto V, Castellani V, Pignatelli P, Pacella E, Mitterhofer AP, Tinti F, Lai S.   +10 more
europepmc   +1 more source

Blocked and “Unblocked” Learning: Structural Factors That Impede and Enable Evidence‐Informed Policymaking

European Policy Analysis, EarlyView.
ABSTRACT This article addresses a critical issue in evidence‐informed policymaking: the challenge of translating knowledge into policy outputs amidst the complex interplay between research and politics. It discusses the concept of “blocked learning,” where individual‐level learning fails to scale up to organizational and policy levels, thus impeding ...
Thenia Vagionaki
wiley   +1 more source

Anorectal incontinence among a working-age population: A cross-sectional survey of prevalence and epidemiology. [PDF]

Colorectal Dis
Balaphas A, Liot E, Delaune V, Meyer J, Gogniat V, Toso C, Meurette G, Vuagnat H, Ris F.   +8 more
europepmc   +1 more source

Predictive value of seizure onset for gross motor dysfunction in individuals with pathogenic GABRB2 and GABRB3 variants

Epilepsia, EarlyView.
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz, Leonardo Affronte, Chiara Bagliani, Serene El‐Kamand, Anthony Sze Hon Kan, Isabel T. Kristoffersen, Rebekka S. Dahl, Anne F. Højte, Stéphane Auvin, Arjan Bouman, Shimriet Zeidler, Gerhard Kluger, Gaetan Lesca, Nicolas Chatron, Zeynep Goke‐Samar, Maria T. Papadopoulou, Matthildi Athina Papathanasiou Terzi, Elise Schaefer, Anne de Saint Martin, Sarah Baer, Mohammed Al Owain, Saud Takroni, Hesham Al‐Dhalaan, Paolo Bonanni, Alessandra Rossi, Nicoletta Zanotta, Marina Trivisano, Nicola Specchio, Angela de Dominicis, Pasquale Striano, Alessandro Orsini, Maria Margherita Mancardi, Sebastian Neuens, Melanie Jennesson‐Lyver, Ira Benkel‐Herrenbrueck, David Genevieve, Richard Sidlow, Kamer Tezcan, Ilona Krey, Johannes R. Lemke, Konrad Platzer, Damien Lederer, Inga Talvik, Ulvi Vaher, Kees P. J. Braun, Anne‐Marie Guerrot, Rebecca More, Matthias De Wachter, Sarah Weckhuysen, Evelina Carapancea, Maria Roberta Cilio, Julia Jacobs, Katalin Sterbova, Simona Balestrini, Renzo Guerrini, Giulio Peroni, Inger‐Lise Mero, Walaa ElNaggar, Nour Elkhateeb, Ariane Schmetz, Denise L. Chan, Ghayda M. Mirzaa, Boris Chaumette, Adrien Legrand, Amy McTague, Tommy Stödberg, Rebekah V. Harris, Samuel F. Berkovic, Ingrid E. Scheffer, Mary Chebib, Elena Gardella, Philip K. Ahring, Nathan L. Absalom, Rikke S. Møller   +73 more
wiley   +1 more source

Decentralized example of a randomized clinical trial: OM-85 use in older patients at risk of respiratory tract infections. [PDF]

Aging Clin Exp Res
Abbatecola AM, Travaglini S, Pedone C, Malara A, Berti A, Vigliotta MT, Pullia R, Elmi D, Ippolito VA, Incalzi RA.   +9 more
europepmc   +1 more source