Results 181 to 190 of about 8,020,688 (229)

Efficacy of stiripentol, fenfluramine, and their combination on clinical outcomes in Dravet syndrome: A preliminary report

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Stiripentol and fenfluramine are approved treatments for Dravet syndrome (DS), but real‐world data comparing their effectiveness and combined use remain limited. Our study aims to explore associations between treatment with stiripentol, fenfluramine, and their combination and clinical outcomes in patients with DS.
Paolo Surdi   +7 more
wiley   +1 more source

Seismic Fragility of Gravity and Semi‐Gravity Retaining Walls and Its Impact on the Functionality Loss of Road Infrastructures

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Retaining walls are key geotechnical components of road infrastructure, whose seismic performance directly affects the resilience of transportation networks. Despite their importance, seismic fragility models for retaining walls available in the literature refer only to specific case studies.
Amendola C., Conti R., de Silva F.
wiley   +1 more source

An Intensity Measure‐Based Methodology for Ground Motion Orientation in Seismic Structural Assessment

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT In current dynamic time history assessment protocols, ground motion recordings are mostly oriented along fixed sensor directions. Consequently, the orientation of the principal resultant of rupture energy, which may control the maximum structural demand, remains undefined, precluding consistent correlation with physically detrimental ...
Santiago Londono‐Lopez   +4 more
wiley   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

open access: yesExploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang   +8 more
wiley   +1 more source

Dynamic epigenetic regulation of BCLAF1 splicing in acute myeloid leukemia. [PDF]

open access: yesCell Death Dis
Sgueglia G   +16 more
europepmc   +1 more source

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

open access: yesFood Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi   +6 more
wiley   +1 more source

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