Results 21 to 30 of about 25,704 (252)

Rome II Regulation

open access: yesInterdisciplinary Management Research VII (IMR 2011): Book of Proceedings, 2011
Despite encouragement and appointment of experts by the EU, only three relevant international treaties regulating EU procedural and private international law were signed in the period from the Treaty of Rome to Treaty of Amsterdam, aperiod lasting 40 years.
openaire   +4 more sources

ВИСВІТЛЕННЯ УПЦ, ПЦУ ТА РПЦ НА ФРАНКОМОВНИХ МЕДІА-РЕСУРСАХ У КОНТЕКСТІ ПОВНОМАСШТАБНОГО ВТОРГНЕННЯ

open access: yesПроблеми семантики, прагматики та когнітивної лінгвістики, 2023
Статтю присвячено дослідженню засобів репрезентації українських православних громад у порівнянні з РПЦ на матеріалі франкомовних новин, опублікованих після 24 лютого 2022 р.
Євгенія Красняк
doaj   +1 more source

Alone on an Island

open access: yesVoices in Bioethics, 2021
Photo by Ferenc Horvath on Unsplash ABSTRACT Malta is a small, predominantly Catholic island-nation in the Mediterranean ocean where there is a complete ban on abortion – there are no exemptions for rape, incest, fetal anomalies, or to save a ...
Erin Kwolek
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019

open access: yesThe Lancet Regional Health. Europe, 2022
Summary: Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed.
Giulio Castelpietra   +113 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Consequences of Brexit for European Private International Law

open access: yesEuropean Papers, 2019
(Series Information) European Papers - A Journal on Law and Integration, 2019 4(1), 395-407 | European Forum Insight of 27 February 2019 | (Table of Contents) I. Introduction. - II.
Johannes Ungerer
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

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