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Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte [PDF]

, 2014
The complex spatial and paracrine relationships between the various liver histotypes are essential for proper functioning of the hepatic parenchymal cells.
Fausto N +6 more
core +3 more sources

Synergistic Enhancement of Antioxidant Activity in Arbutus unedo Leaf Extract by Biological Fluids: Implications for Functional and Nutraceutical Applications

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This study examined the effect of biological fluids (saliva, blood plasma, and urine) on the antioxidant capacity of an aqueous extract derived from Arbutus unedo leaves. The extract displayed a concentration‐dependent reducing activity in the ferric reducing power assay (IC50 = 292 ± 7.54 µg/mL) and phosphomolybdenum assays (IC50 = 461.67 ± 4.
Idir Moualek +6 more
wiley +1 more source

The Significance of the Rome Ii Regulation in the Unification Process of the European Union [PDF]

European Journal of Law and Public Administration, 2019
Legislative activity of the European Union (EU) came close to embodying the idea of creating the EU Code of Private Law, although traditionally questions of private international law have always been within the scope of regulation of national legislation.
openaire +1 more source

6th International Symposium on Molecular Allergology (ISMA)

Clinical and Translational Allergy, 2016
Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic ...
Christiane Hilger +471 more
doaj +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta +5 more
wiley +1 more source

Cross-border Products Liability in the European Union

Derecho PUCP, 2015
Liability for defective products meets a modern legal framework applicable to cases which have an international nature in the European Union. However, the new regulatory developments have not solved the existing coordination problems and offer an ...
Guillermo Palao Moreno
doaj

Cannabinoids in the Treatment of Epilepsy: Current Status and Future Prospects

Neuropsychiatric Disease and Treatment, 2020
Alessandra Morano,1 Martina Fanella,1 Mariarita Albini,1 Pierangelo Cifelli,2,3 Eleonora Palma,2 Anna Teresa Giallonardo,1 Carlo Di Bonaventura1 1Epilepsy Unit, Department of Human Neurosciences, “Sapienza” University of Rome, Rome, Italy ...
Morano A +6 more
doaj

Main factors associated with variability in the assessment of the objective response rate. A re‐analysis of the PHEREXA phase 3 clinical trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Local investigators (LIs) overestimate the objective response rate (ORR) in comparison to Blinded Independent Central Reviewers (BICR) in oncology. In this study, we re‐analysed data obtained in the PHEREXA trial (NCT01026142) with the following aims: i) to confirm at the single‐patient level the discrepancy observed by analysing ...
Gennaro Daniele +3 more
wiley +1 more source

Selected Abstracts of the 4th International Congress of UENPS; Athens (Greece); December 11th-14th 2014

Journal of Pediatric and Neonatal Individualized Medicine, 2014
Selected Abstracts of the 4th International Congress of UENPS • Athens (Greece) • December 11th-14th 2014 The Congress has been organized by the Union of European Neonatal and Perinatal Societies (UENPS).
--- Various Authors
doaj +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source

16. peace & justice
choice of law
applicable law

private international law
regulation rome ii
romeiiregulation

law
lex loci damni
habitual residence