Results 11 to 20 of about 3,281 (174)

A multicenter study of romiplostim for chemotherapy-induced thrombocytopenia in solid tumors and hematologic malignancies [PDF]

open access: yesHaematologica, 2020
Chemotherapy-induced thrombocytopenia (CIT) frequently complicates cancer treatment causing chemotherapy delays, dose reductions, and discontinuation. There is no FDA-approved agent available to manage CIT.
Hanny Al-Samkari   +5 more
doaj   +2 more sources

Uso de romiplostim en trombocitopenia inmunitaria: experiencia en Cuenca (Ecuador) [PDF]

open access: yesBiomédica: revista del Instituto Nacional de Salud
Introducción. El consenso internacional y la guía del 2019 de la American Society of Hematology, establecieron a los análogos de la trombopoyetina como medicamentos de segunda línea para tratar la trombocitopenia inmunitaria primaria.
Héctor Chiang-Wong   +1 more
doaj   +2 more sources

Romiplostim-associated increase in CD34+ megakaryocytes in a case of immune thrombocytopenia: A case report

open access: yesHuman Pathology Reports, 2023
We report a patient with chronic immune thrombocytopenia purpura who underwent bone marrow biopsies before and after treatment with romiplostim. The biopsy after treatment with romiplostim showed a marked increase in the numbers of megakaryocytes which ...
Charles M. Lombard   +2 more
doaj   +2 more sources

Romiplostim in chemotherapy‐induced thrombocytopenia: A review of the literature

open access: yesCancer Medicine
Chemotherapy‐induced thrombocytopenia (CIT) is a common challenge of cancer therapy and can lead to chemotherapy dose reduction, delay, and/or discontinuation, affecting relative dose intensity, and possibly adversely impacting cancer care.
Gerald A. Soff   +4 more
doaj   +2 more sources

Romiplostim for thrombocytopenia following allogeneic stem cell transplantation: A case series

open access: yesHematology/Oncology and Stem Cell Therapy, 2020
Thrombocytopenia is a relatively common complication following allogeneic hematopoietic stem cell transplantation and is associated with increased bleeding, transfusion requirements, chronic graft-versus-host disease, and all-cause mortality.
Guido Lancman   +2 more
doaj   +2 more sources

Romiplostim for treatment of thrombocytopenia in dogs: A retrospective assessment and clinical outcomes

open access: yesJournal of Veterinary Internal Medicine
Background Romiplostim, a thrombopoietin analog, is commonly used to treat immune‐mediated thrombocytopenia (ITP) in humans, but its use in dogs remains limited.
Min‐Ok Ryu   +5 more
doaj   +2 more sources

Is There a Role for Biweekly Romiplostim in the Management of Chronic Immune Thrombocytopenia (ITP)? A Report of Three Cases

open access: yesCase Reports in Hematology, 2018
Romiplostim is a peptibody, which stimulates platelet production by a mechanism similar to that of endogenous thrombopoietin. It has an established indication as second-line therapy in patients with chronic immune thrombocytopenia (ITP).
Jasjit Kaur Rooprai, Karima Khamisa
doaj   +2 more sources

Romiplostim use for thrombocytopenia following allogeneic hematopoietic stem cell transplantation: a case series from a single center in Qatar

open access: yesHematology, 2023
Thrombocytopenia is a common and serious complication that can occur following hematopoietic stem cell transplantation (HSCT), and it contributes to increased morbidity and mortality.
Abdulrahman F. Al-Mashdali   +3 more
doaj   +2 more sources

Total remission of severe immune thrombocytopenia after short term treatment with romiplostim

open access: yesHematology Reports, 2011
Immune thrombocytopenia (ITP) in adults is an acquired chronic immune-mediated disorder defined by isolated thrombocytopenia. In recent years, an improved understanding of the pathophysiology of ITP has been achieved and is now accepted that the disorder
Efthymia Vlachaki   +6 more
doaj   +2 more sources

Long-term safety and efficacy of romiplostim for treatment of immune thrombocytopenia

open access: yesJournal of Blood Medicine, 2016
Prakash Vishnu,1 David M Aboulafia1,2 1Floyd and Delores Jones Cancer Institute at Virginia Mason Medical Center, 2Division of Hematology, University of Washington, Seattle, WA, USA Abstract: Inhibition of platelet production and mediated by ...
Vishnu P, Aboulafia DM
doaj   +1 more source

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