Results 191 to 200 of about 93,916 (326)

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Heterojunction interface-engineered SnO₂-CuO SAW sensor for room-temperature CO₂ detection with fast response and high selectivity. [PDF]

Microsyst Nanoeng
Jin J, Yang Q, Hu A, Cui B, Xue X, Liang Y, Shi F, Lee K, Wang W.   +8 more
europepmc   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

Advanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu, Yating Wang, Siming Jiang, Yi Li, Guanglan Li, Yuchu Liu, Siyuan Li, Yiming Zhou, Qinghua Liu, Yi Zhou, Wei Chen, Hongyu Li, Haiping Mao   +12 more
wiley   +1 more source

Correction of computational artifacts in numerical solving of diffusion equation for room acoustics

, 2012
Jaroslaw Kraszewski, Andrzej Dobrucki
openalex   +1 more source

Near‐Field Acoustic Imaging Using Fiber‐Optic Distributed Acoustic Sensing and Beamforming Techniques

Advanced Science, EarlyView.
This work introduces a beamforming‐based method to generate acoustic images from fiber‐optic distributed acoustic sensing (DAS) data. By performing 2D scanning around the sensing fiber, the approach enables near‐field imaging and localization of acoustic sources, even in regions distant from the fiber. A data‐driven DAS channel selection improves image
Marcelo A. Soto, Diego Badillo‐San‐Juan   +1 more
wiley   +1 more source

Orbital angular momentum- and frequency-dependent high-capacity encrypted hologram through multi-dimensional multiplexing acoustic metasurface. [PDF]

Nat Commun
Zhou YQ, Li F, Wu K, Wang W, Liu J, Liang B, Cheng JC.   +6 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Optimization strategy for sound environment of college basketball stadium. [PDF]

PLoS One
Liang J.
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Speech motor control is not sequestered from general auditory processes. [PDF]

J Exp Psychol Gen
Thorburn C, Zhou L, Dick F, Nozari N, Holt LL.   +4 more
europepmc   +1 more source