Results 61 to 70 of about 4,716 (257)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Perception of the Mother- and Baby-Friendly Hospital Initiative (MBFHI) in Cartagena, Colombia, 2012
Revista Ciencias de la Salud, 2015 Objective: To establish the perception level of the implementation of the BFHI initiative steps in health institutions in Cartagena in 2012. Material and methods: Descriptive study in a population constituted by 21 public and private institutions, as ...
Rossana López Sáleme +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Postpartum women’s level of comprehension of newborn care instructions at a rooming-in facility
Clinical and Biomedical Research, 2017 Introduction: This study aimed to assess the postpartum women’s level of comprehension of newborn care practices taught at a rooming-in facility. Methods: In this cross-sectional study, a Likert scale was used to assess the participants’ level of ...
Bruna Cabrera Dauber +1 more
doaj +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Perception of the father about paternity in rooming-in-care
Revista de Enfermagem da Universidade Federal de Santa Maria, 2017 Aim: to comprehend the parental perception about the father’s support during the hospitalization of his wife and son in the rooming-in-care. Method: descriptive and exploratory qualitative approach, in the maternity of a private hospital inPorto Alegre ...
Márcia Rejane Strapasson +5 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Breastfeeding Practices for COVID-19-Infected Mothers: A Systematic Review and Meta-Analysis
Nursing Reports(1) Background: The ongoing COVID-19 pandemic has led to an increasing number of women giving birth while also grappling with SARS-CoV-2. The objective of this review is to examine the possibility of transmission of the virus from mother to infant ...
Maria Eleni Boukoura +6 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source