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Marketing Strategy for New Venture in Information Technology Education (Online Tutorial – TUTON) [PDF]

open access: yes, 2013
Indonesia has a rapid development in Information Technology (IT) as well as the public interest to learn it. However, to find qualified employee in IT is difficult, they often lacks proper education in IT background. IT education is not only need quality,
Larso, D. (Dwi), Lubis, E. H. (Esty)
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Patterns of unexpected in-hospital deaths: a root cause analysis

open access: yesPatient Safety in Surgery, 2011
Background Respiratory alarm monitoring and rapid response team alerts on hospital general floors are based on detection of simple numeric threshold breaches.
Curry J Paul, Lynn Lawrence A
doaj   +1 more source

Root cause analysis and health informatics [PDF]

open access: yes
Root Cause Analysis (RCA) is the most widely used system analysis tool for investigating safety related incidents in healthcare. This contribution reviews RCA techniques, using a Health Informatics example, and discusses barriers to their successful ...
Despotou, George, Jones, Richard W.
core  

Reducing Late-Timing Failure at Scale: Straggler Root-Cause Analysis in Cloud Datacenters [PDF]

open access: yes, 2016
Task stragglers hinder effective parallel job execution in Cloud datacenters, resulting in late-timing failures due to the violation of specified timing constraints.
Garraghan, P   +4 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Improving Education as Key to Enhancing Adaptive Capacity in Developing Countries [PDF]

open access: yes
This paper summarizes new scientific evidence supporting the hypothesis that among the many factors contributing to international development, the combination of education and health stands out as a root cause on which other dimensions of development ...
Wolfgang Lutz
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Teaching Root Cause Analysis Using Simulation: Curriculum and Outcomes

open access: yesJournal of Medical Education and Curricular Development, 2019
Background: Clinicians are key drivers for improving health care quality and safety. However, some may lack experience in quality improvement and patient safety (QI/PS) methodologies, including root cause analysis (RCA).
Maya Aboumrad   +2 more
doaj   +1 more source

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