Results 41 to 50 of about 389,388 (249)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Leveraging multi-agent framework for root cause analysis

open access: yesComplex & Intelligent Systems
RCA is critical for operational stability in complex integrated systems, such as cloud-native platforms and distributed power metering infrastructures. However, achieving automated RCA faces three fundamental challenges: (1) the complex mapping between ...
Feng Fu   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigation of Medication Safety Incidents Using Root Cause Analysis and Action [PDF]

open access: yesGlobal Journal on Quality and Safety in Healthcare, 2021
Ghada Hussain Al Mardawi   +1 more
doaj   +1 more source

Exploring the Causes of Power-Converter Failure in Wind Turbines based on Comprehensive Field-Data and Damage Analysis

open access: yesEnergies, 2019
Power converters are among the most frequently failing components of wind turbines. Despite their massive economic impact, the actual causes and mechanisms underlying these failures have remained in the dark for many years.
Katharina Fischer   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Application of root cause analysis technique in surgery: A qualitative study of weaknesses, strengths and challenges

open access: yesبیمارستان, 2021
Introduction: Root cause analysis is one of the most important tools in disaster management that aims to identify the real causes of an issue and find ways to eliminate them.
Sepideh Safaverdikhan   +2 more
doaj  

Exploring Exploratory Data Analysis: An Empirical Test of Run Chart Utility

open access: yesManagement Systems in Production Engineering, 2023
This paper explores Exploratory Data Analysis (EDA). Graphical methods are used to gain insights in EDA and these insights can be useful for forming tentative hypotheses when performing a root cause analysis (RCA).
Barsalou Matthew   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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