Results 121 to 130 of about 1,313,062 (313)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Species interactions enhance root allocation, microbial diversity and P acquisition in intercropped wheat and soybean under P deficiency

, 2017
Adnane Bargaz, Genevieve L. Noyce, Roberta R. Fulthorpe, Georg Carlsson, Jessie R. Furze, Erik Steen Jensen, Driss Dhiba, Marney E. Isaac   +7 more
openalex   +2 more sources

Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancer [PDF]

, 2014
Suzanna M. Zick, D. Kim Turgeon, Jianwei Ren, Mack T. Ruffin, Benjamin D. Wright, Ananda Sen, Zora Djurić, Dean E. Brenner   +7 more
openalex   +1 more source

Root, Root, Root for the Home Team [PDF]

Nature Biotechnology, 1985
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

PERFORMANCE OF TARO UNDER LOWLAND CONDITION AS AFFECTED BY GENOTYPE, NUTRITIONAL STATUS AND POPULATION DENSITY

Annals of Tropical Research, 1982
The local taro variety Kalpao performed better than the Introduced variety Big Lehua. Kalpao had higher yield, shorter growing period and was relatively resistant to adverse growing conditions than Big Lehua.
JR Pardales Jr., MR Villanueva, FR Cotejo Jr.   +2 more
doaj  

Response of Soybean Root to Phosphorus Deficiency under Sucrose Feeding: Insight from Morphological and Metabolome Characterizations [PDF]

, 2020
Ahui Yang, Lingjian Kong, Hui Wang, Xingdong Yao, Futi Xie, Haiying Wang, Xue Ao   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A wheat/rye polymorphism affects seminal root length and yield across different irrigation regimes [PDF]

, 2019
T. A. Howell, Jorge I. Moriconi, Xueqiang Zhao, Joshua Hegarty, Tzion Fahima, Guillermo E. Santa-Marı́a, Jorge Dubcovsky   +6 more
openalex   +1 more source