Results 151 to 160 of about 3,751,965 (346)

Natural variation of hormone levels in Arabidopsis roots and correlations with complex root architecture

Journal of Integrative Plant Biology, 2018
Studies on natural variation are an important tool to unravel the genetic basis of quantitative traits in plants. Despite the significant roles of phytohormones in plant development, including root architecture, hardly any studies have been done to ...
Sangseok Lee, Lidiya I. Sergeeva, D. Vreugdenhil   +2 more
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Phosphate-Solubilizing Bacteria and Phosphorus Fertilization Shape Microbial Dynamics in the Maize Rhizosphere

Diversity
The use of bioinoculants aligns with ecological intensification in agriculture, but their effects on crop performance and soil microbiota under different fertilization regimes remain unclear.
Raquel Gomes de Oliveira, Ubiraci Gomes de Paula Lana, Christiane Abreu de Oliveira-Paiva, Mariana Lourenço Campolino, João Vitor Silvério Alves de Avelar, Eliane Aparecida Gomes, Thiago Teixeira Santos, Flavia Cristina dos Santos, Sylvia Morais de Sousa Tinôco   +8 more
doaj   +1 more source

Modulating root system architecture: cross-talk between auxin and phytohormones

Frontiers in Plant Science
Root architecture is an important agronomic trait that plays an essential role in water uptake, soil compactions, nutrient recycling, plant–microbe interactions, and hormone-mediated signaling pathways.
Mehmood Jan, Sajid Muhammad, Weicai Jin, Wenhao Zhong, Shaolong Zhang, Yanjie Lin, Yueni Zhou, Jinlong Liu, Haifeng Liu, Raheel Munir, Qiang Yue, Muhammad Afzal, Guoping Wang   +12 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Effects of Different Soil Phosphorus Levels on the Physiological and Growth Characteristics of Phyllostachys edulis (Moso Bamboo) Seedlings

Plants
Soil phosphorus (P) availability is a critical factor affecting the productivity of Phyllostachys edulis (moso bamboo) forests. However, the mechanisms underlying the physiological and growth responses of moso bamboo to varying soil P conditions remain ...
Zhenya Yang, Benzhi Zhou
doaj   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The Architecture of MEG Simulation and Analysis Software

, 2011
MEG (Mu to Electron Gamma) is an experiment dedicated to search for the $\mu^+ \rightarrow e^+\gamma$ decay that is strongly suppressed in the Standard Model but predicted in several Super Symmetric extensions of it at an accessible rate.
G. Corti, G.J. Feldman, J. Adam, R. Brun, R. Brun, S. Ritt   +5 more
core   +1 more source