Results 151 to 160 of about 1,509,050 (359)

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

open access: yesAdvanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao   +8 more
wiley   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh   +8 more
wiley   +1 more source

Irrigation solutions in endodontic treatmen

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2013
Introduction: Elimination of pathogens from root canal system is the goal of endodontic treatment. Cleaning and shaping the root canal system is one of the most important steps in root canal therapy.
Abbasali Khademi   +2 more
doaj  

High‐Speed, Maneuverable, and Terrain‐Adaptive Micro‐Robot with Tree Frog‐Inspired Bionic Feet

open access: yesAdvanced Science, EarlyView.
A 7.5 mm micro‐robot integrates tree frog‐inspired bionic feet with an electromagnetic linear motor to achieve high‐speed locomotion, slope climbing, and precise turning. It reaches 39 body lengths per second and ascends 30° slopes. The system demonstrates strong potential for inspection tasks in confined and complex environments, such as micro‐aero ...
Weizhi Zhao   +10 more
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

open access: yesAdvanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao   +13 more
wiley   +1 more source

Maleic acid as a root canal irrigant- a scoping review. [PDF]

open access: yesBMC Oral Health
Kapur T   +4 more
europepmc   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira   +18 more
wiley   +1 more source

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