Results 41 to 50 of about 1,509,050 (359)

Biocompatibility of Root Canal Sealers: A Systematic Review of In Vitro and In Vivo Studies

open access: yesMaterials, 2019
(1) Aim: To perform a systematic review of the literature on the biocompatibility of root canal sealers that encompasses the various types of sealers that are commercially available as well as both in vitro and in vivo evidence.
Diogo Fonseca   +7 more
semanticscholar   +1 more source

Bioactive Glass-Based Endodontic Sealer as a Promising Root Canal Filling Material Without Semisolid Core Materials

open access: yesMaterials, 2019
Endodontic treatment for a tooth with damaged dental pulp aims to both prevent and cure apical periodontitis. If the tooth is re-infected as a result of a poorly obturated root canal, periapical periodontitis may set-in due to invading bacteria.
A. Washio   +3 more
semanticscholar   +1 more source

Numerical simulation of nanofluid flow inside a root canal

open access: yes, 2019
Silver nano particles have antimicrobial property which makes them appropriate for disinfection. Due to their antimicrobial feature, these particles are applicable for root canal irrigation.
Mohammad Ghalandari   +4 more
semanticscholar   +1 more source

Unprepared root canal surface areas: causes, clinical implications, and therapeutic strategies.

open access: yesBrazilian Oral Research, 2018
Chemomechanical preparation is intended to clean, disinfect, and shape the root canal. This step is of utmost importance during treatment of infected teeth with apical periodontitis, because treatment outcome depends on how effectively the clinician ...
J. S. Siqueira Junior   +4 more
semanticscholar   +1 more source

Effects of different root canal filling stop on quality of root canal filling in root canals obturated with Gutta⁃ Flow

open access: yes口腔疾病防治, 2018
Objective To investigate the effects of different root canal filling stop on quality of root canal filling and apical sealing in root canals obturated with GuttaFlow.
YANG Weidong
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Prevalence of middle mesial root canal in mandibular molars in an Iranian population: A micro-computed tomography study

open access: yesDental Research Journal
Background: Knowledge about the anatomic variations of the root canal system and their prevalence is necessary for clinicians to ideally clean the root canal system.
Alireza Farhad   +3 more
doaj   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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