Results 41 to 50 of about 68,650 (262)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Caspian journal of dental research, 2015 Introduction: Root canal instrumentation is an important phase in root canal therapy. Since success in endodontic treatment depends on file defect and fracture, the aim of this study was to compare the evaluation of defect and fracture in rotary and ...
Mahdis Bagherian +6 more
doaj
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Mandibular first premolar with five root canals: a case report
BMC Oral Health, 2020 Background Understanding the anatomical morphology of the root canal is key for successful root canal treatment. The aims of this case presentation are to report a unique case of root canal treatment involving five root canals in the mandibular first ...
Ming Zhang +3 more
doaj +1 more source
Root canal morphology of primary molars by clearing technique: An in vitro study
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2018 Objective: The objective of the study was to study root canal morphology of primary molars by clearing technique and to observe for any variations. Materials and Methods: One hundred and twenty extracted primary molars were divided into four groups (n ...
Farhin Katge, Mayur Manohar Wakpanjar
doaj +1 more source
Light‐Actuated Fiber‐Climbing Inchworm Robot Toward Endoluminal Navigation
Advanced Functional Materials, EarlyView.A kirigami‐inspired soft inchworm robot harnesses optical energy from a customized side‐emitting optical fiber, guaranteeing its propulsion along the fiber body. The wavelength‐selective responsiveness of dye‐functionalized liquid crystal elastomers and the application of temporal illumination patterns enable sequential control of robot components. The
Antonio Lobosco +6 more
wiley +1 more source
Mandibular left first premolar with two roots: A morphological oddity
Contemporary Clinical Dentistry, 2012 Thorough knowledge of the root canal morphology, appropriate assessment of the pulp chamber floor, and critical interpretation of radiographs are a prerequisite for successful root canal therapy.
Nitin Kararia +2 more
doaj +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source