Results 141 to 150 of about 1,467,829 (302)

Description of the root anatomy of the primary molars using high resolution computed microtomography (Micro-CT). An analysis of three-dimensional root canal system [PDF]

Background/purposeThis study aimed to describe the root canal morphology of primary molars using Micro-CT and analyse the three-dimensional images of the internal root canal system.Material and methodsOne hundred and twenty extracted primary molars with ...
Cristina Rico-Romano, Cristina Obispo-Diaz, Benedetta Vidi, Ana María Gil-Valcarcel, Jesús Mena-Álvarez, Isabel Sanchez-Jorge, Juan Manuel Aragoneses-Lamas, Sanchez-Jorge, Isabel, Obispo-Diaz, Cristina, Obispo Diaz, Cristina, Rico Romano, Cristina, Sánchez Jorge, María Isabel, Vidi, Benedetta, Mena-Álvarez, Jesús, Aragoneses, Juan Manuel, Mena Álvarez, Jesús, Aragoneses-Lamas, Juan Manuel, Rico-Romano, Cristina, Gil Valcárcel, Ana María, Gil-Valcarcel, Ana María   +19 more
core   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Root Canal Anatomy of Myanmar Permanent Mandibular Incisors in Mandalay Region. [PDF]

Int J Dent, 2020
Aung NM.
europepmc   +1 more source

Electrophoretic Deposition of Bioactive Nanoparticles for Disinfection of Apical Root Canal Anatomy [PDF]

, 2019
Objective: To utilize the principles of electrophoresis to transport and deposit cationic nanoparticles in apical root canal anatomy for enhanced antibacterial effect. Materials and Methods: The novel technological approach was assessed in two phases: i)
Harris, David
core  

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Endodontic Management of Maxillary Central Incisor with Rare Root Canal Anatomy. [PDF]

Cureus, 2020
Yadav S, Nawal RR, Talwar S.
europepmc   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Root canal anatomy of human permanent mandibular incisors and mandibular canines: A systematic review.

J Conserv Dent, 2022
Dhuldhoya DN, Singh S, Podar RS, Ramachandran N, Jain R, Bhanushali N.   +5 more
europepmc   +1 more source