Results 51 to 60 of about 31,250 (335)

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

In vitro analysis of thermocompaction time and gutta-percha type on quality of main canal and lateral canals filling

Brazilian Oral Research, 2010
The aim of this study was to evaluate the quality of filling in main and lateral root canals performed with the McSpadden technique, regarding the time spent on the procedure and the type of gutta-percha employed.
André Luiz da Costa Michelotto, Cacio Moura-Netto, Ângela Toshie Araki, Eduardo Akisue, Abílio Albuquerque Maranhão Moura, Gilson Blitzkow Sydney   +5 more
doaj   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

Advanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani, Shiyu Liu, Evan Johnston, Weiyi Wan, Xiaoyi Lan, Tianqin Ning, Alexander Nottegar, Ran Huo, Shuaibing Jiang, Jianyu Li   +9 more
wiley   +1 more source

Penetration of bioceramic and epoxy-resin endodontic cements into lateral canals

Brazilian Oral Research
: The aim of the present study was to assess the penetration capacity of two endodontic cements, Endosequence BC Sealer and AH Plus, in artificial lateral canals.
George Táccio de Miranda Candeiro, Amanda Bezerra Lavor, Ilana Thaís de Freitas Lima, Bruno Carvalho de Vasconcelos, Nilton Vivacqua Gomes, Elaine Faga Iglecias, Giulio Gavini   +6 more
doaj   +1 more source

Antimicrobial Efficacy of Medicated Root Canal Filling Materials

Journal of Endodontics, 2006
Bacteria remaining within the root canal system are a significant factor in endodontic failures. The aim of this in vitro study was to evaluate the antimicrobial efficacy of commercially available gutta-percha formulations against common endodontic pathogens. Standard, tetracycline, or iodoform (also called medicated gutta-percha; MGP) containing gutta-
Department of Endodontics, Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, Florida ( host institution ), Melker, Kevin B. ( author ), Vertucci, Frank J. ( author ), Rojas, Maria Fernanda ( author ), Progulske-Fox, Ann ( author ), Bélanger, Myriam ( author )   +5 more
openaire   +4 more sources

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Clinical and radiographic evaluation of pulpectomies using three root canal filling materials: an in-vivo study.

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2010
Various root canal filling materials are used to preserve a pulpally involved carious primary tooth. But there is no single material so far available to fulfill all the requirements of an ideal root canal filling material for a primary tooth.
K. Ramar, J. Mungara
semanticscholar   +1 more source

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

Advanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi, Anastasiya Börsch, Paola Occhetta, Robert Ivanek, Martin Ehrbar, Lisa Krattiger, Philipp Oertle, Marko Loparic, Ivan Martin, Marco Rasponi, Andrea Barbero   +10 more
wiley   +1 more source

Odontogenic fungus maxillary sinusitis. Report of a clinical case

Эндодонтия Today, 2020
In a 21-year-old woman, a sinusitis maxillaris resulting from overextension of root canal filling material after an endodontic treatment of a maxillary molar could be diagnosed through computed tomography.

doaj  

Resilon: A Comprehensive Literature Review

Journal of Dental Research, Dental Clinics, Dental Prospects, 2013
Bonding to dentin is a promising property, which can prevent leakage and improve the sealing ability of endodontic filling materials. Resilon was developed and recommended initially because the existing root canal filling materials did not bond to root
Mehrdad Lotfi, Negin Ghasemi, Saeed Rahim, Sepideh Vosoughhosseini, Mohammad Ali Saghiri, Atabak Shahidi   +5 more
doaj   +1 more source