Results 141 to 150 of about 2,774 (214)

Mastoid Surgery Does Not Normalize Tympanometric Middle Ear Pressure in Children With Cholesteatoma

open access: yesThe Laryngoscope, Volume 136, Issue 6, Page 2719-2726, June 2026.
Conflicting mechanism‐based hypotheses have been used to promote selection of different approaches to management of the mastoid in order to optimize middle ear pressure homeostasis after removal of cholesteatoma. For example: (a) conservation of mastoid mucosa and opening of ventilation pathways endoscopically to normalize function, (b) removal of ...
Adrian L. James
wiley   +1 more source

Unraveling Oral Dysbiosis: Microbial Complexity in Common Oral Diseases

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The oral microbiome undergoes dynamic establishment from birth, maturing into a resilient ecosystem. Perturbation of this homeostasis—driven by dietary, immunological, and anatomical factors—triggers dysbiosis, which underpins the pathogenesis of major oral diseases, including dental caries, periodontal disease, salivary gland disorders, oral mucosal ...
Zixi Kang   +8 more
wiley   +1 more source

Influence of Limited Mouth Opening on Guided Endodontic Access and Its Clinical Management: A Case Report. [PDF]

open access: yesIran Endod J
Junior GM   +6 more
europepmc   +1 more source

Gastric Cancer: Pathobiology and Therapeutics

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Gastric cancer is a multistep process driven by the interplay of microbial virulence, host epithelial injury, and evolving molecular reprogramming. Initiation involves pathogen‐induced epigenetic alterations and the early subversion of key oncogenic signaling networks, facilitating the transition from chronic injury to metaplasia and malignant ...
Ruixian Yu   +16 more
wiley   +1 more source

Defining the Timing of Radiological Follow‐Up for Detection of Cholesteatoma Recidivism: A Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 174, Issue 6, Page 1410-1420, June 2026.
Abstract Objective Non‐echo‐planar diffusion‐weighted imaging (non‐EPI DWI) magnetic resonance imaging (MRI) has revolutionized postoperative cholesteatoma follow‐up, shifting from surgical to radiological evaluation. Yet, the timing for postoperative imaging remains contentious.
Amit Wolfovitz   +4 more
wiley   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

open access: yesVIEW, Volume 7, Issue 3, June 2026.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie   +9 more
wiley   +1 more source

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