Results 101 to 110 of about 78,689 (263)

scHeteroNet: A Heterophily‐Aware Graph Neural Network for Accurate Cell Type Annotation and Novel Cell Detection

open access: yesAdvanced Science, EarlyView.
scHeteroNet) is a novel graph neural network model that explicitly addresses heterophily in single‐cell sequencing data enabling accurate cell type annotation and novel cell type discovery. By leveraging heterophily‐aware message passing and novelty propagation mechanisms, scHeteroNet achieves superior performance in both cell annotation and detection ...
Jiacheng Liu   +7 more
wiley   +1 more source

Ex Vivo Comparison of Mtwo and RaCe Rotary File Systems in Root Canal Deviation: One File Only versus the Conventional Method

open access: yesFrontiers in Dentistry, 2016
Objectives: Cleaning and shaping of the root canal system is an important step in endodontic therapy. New instruments incorporate new preparation techniques that can improve the efficacy of cleaning and shaping.
Mohsen Aminsobhani   +2 more
doaj  

ProTaper rotary root canal preparation: assessment of torque and force in relation to canal anatomy [PDF]

open access: bronze, 2003
Ove A. Peters   +3 more
openalex   +1 more source

A Molecularly Defined Medullary Network for Control of Respiratory Homeostasis

open access: yesAdvanced Science, EarlyView.
The dynamic interplay between central respiratory chemoreceptors and the respiratory central pattern generator is essential for maintaining stable respiratory rhythm and patterns, particularly during sleep. This study offers novel insights into the anatomical, molecular, and functional characteristics of a medullary network involving the nucleus ...
Tianjiao Deng   +16 more
wiley   +1 more source

Evaluation of Mechanical Versus Manual Root Canal Preparation in Primary Molars-A Comparative In Vitro Study. [PDF]

open access: yesJ Clin Med, 2023
Schulz-Weidner N   +7 more
europepmc   +1 more source

On Analysis And Generation Of Biologically Important Boolean Functions [PDF]

open access: yesarXiv, 2014
Boolean networks are used to model biological networks such as gene regulatory networks. Often Boolean networks show very chaotic behavior which is sensitive to any small perturbations.In order to reduce the chaotic behavior and to attain stability in the gene regulatory network,nested canalizing functions(NCF)are best suited NCF and its variants have ...
arxiv  

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang   +17 more
wiley   +1 more source

In vivo microbiological evaluation of the effect of biomechanical preparation of root canals using different irrigating solutions [PDF]

open access: diamond, 2006
Mário Tanomaru‐Filho   +5 more
openalex   +1 more source

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao   +14 more
wiley   +1 more source

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