Results 101 to 110 of about 108,992 (308)

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

Torsion and Bending Properties of EdgeEndo Files [PDF]

, 2016
Introduction: One important step of root canal therapy is the process of cleaning and shaping each canal. This process involves using endodontic rotary files combined with chemical irrigants to remove pulpal remnants and infected dentin from the canal ...
Hansen, Chad
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Ex Vivo Comparison of Mtwo and RaCe Rotary File Systems in Root Canal Deviation: One File Only versus the Conventional Method

Frontiers in Dentistry, 2016
Objectives: Cleaning and shaping of the root canal system is an important step in endodontic therapy. New instruments incorporate new preparation techniques that can improve the efficacy of cleaning and shaping.
Mohsen Aminsobhani, Hasan Razmi, Solmaz Nozari   +2 more
doaj  

Fracture Resistance of Compromised Endodontically Treated Teeth Restored with Bonded Post and Cores: An in Vitro Study [PDF]

, 2015
Statement of problem: It is unclear which post and core system performs best when bonded to severely compromised endodontically treated teeth. Purpose: The purpose of this study was to investigate the fracture resistance and mode of failure of severely ...
Kontogiorgos, Elias D., Maroulakos, Georgios, Nagy, William W.   +2 more
core   +2 more sources

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Efficacy of Gel- and Solution-Based Formulations of Conventional Endodontic Disinfectants During Root Canal Shaping: A Systematic Review of Laboratory and Clinical Studies

European Endodontic Journal
This systematic review aimed to evaluate the comparative efficacy of gel-based versus solution-based formulations during root canal shaping in terms of smear layer and debris removal, instrument separation, file fatigue, bacterial reduction,debris ...
Kavalipurapu Venkata Teja, Kaligotla Apoorva Vasundhara, Athina Christina Georgiou, Gianrico Spagnuolo, Luigi Esposito, Niccoló Giuseppe Armogida   +5 more
doaj   +1 more source

Mineral trioxide aggregate repair of lateral root perforation using intentiional replantation and bone grafting [PDF]

, 2011
Root perforation is a significant complication during root canal treatment. Root perforation can result in loss of integrity of the root structure and severe periodontal and bone defect. Repair of lateral root perforation presents a clinical challenge to
Chan, AWK, Dissanayaka, WL, Zhang, C
core  

Bilateral mandibular canines with two roots and two separate canals: case report [PDF]

, 2009
The mandibular canine is usually considered a single-rooted tooth with a single root canal. However, two canals and more rarely two roots may also occur.
BALDI, Jarcio Victorio, BERNARDES, Ricardo Affonso, BERNARDINELLI, Norberti, BRAMANTE, Clovis Monteiro, GARCIA, Roberto Brandão, MORAES, Ivaldo Gomes de, VICTORINO, Fausto Rodrigo   +6 more
core   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source