Influence of Clinical Operative Technique on Debris Extrusion of Two Reciprocating Files
Objective: To compare the influence of different clinical operative motions (pecking motion vs. MIMERACI) on apical debris extrusion using WaveOne Gold and EdgeOne Fire reciprocating files in the mesiobuccal canal of extracted molars.
Ayfer Atav Ates +5 more
doaj
The aim of this study was to compare the amount of irrigant extrusion in simulated immature permanent teeth when the apical diameter and needle insertion depth were varied.
AKSEL Hacer +3 more
doaj +1 more source
Shaping ability of four root canal instrumentation systems in simulated 3D-printed root canal models. [PDF]
INTRODUCTION:The aim of this study was to compare the shaping ability of four root canal preparation systems in newly developed 3D-printed root canal models.
David Christofzik +5 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Cone Beam Computed Tomographic Assessment of Canal Transportation and Centric Ability After Using Different Rotary File Systems in Curved Canals [PDF]
Introduction: Cleaning and shaping of the root canal system are crucial steps in endodontic treatment. However, canal transportation is a frequent procedural error encountered during the preparation of curved canals.
Sabah Sobhy, Hanaa Mansy
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
An Aseptic Root-Canal Technic for the Preparation and Filling of Root-canals [PDF]
n ...
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source

