Results 111 to 120 of about 124,431 (375)
USING PHOTODYNAMIC THERAPY IN ROOT CANAL SYSTEM – A LITERATURE REVIEW
, 2021 Microorganisms do play in pulpal and periapical infection. Success of endodontic treatment aims at effective eradication of bacteria from the root canal space. This, in turn, prevents further microbial recolonization. Persistent microbial colonies in the
P, AJITHA
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Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Pesquisa Brasileira em Odontopediatria e Clínica IntegradaObjective: To compare the amount of debris extruded apically between various root canal instrumentation techniques. Material and Methods: 60 extracted human premolars were randomly divided into 4 groups (n= 15).
Thulficar Ghali Hameed Al-Khafaji +4 more
doaj
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Advanced Science, EarlyView.Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
wiley +1 more source
Análise pelo MEV da remoção da lama dentinária após o preparo dos canais radiculares de dentes decíduos [PDF]
, 2007 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Odontologia.A presente pesquisa teve como objetivo avaliar em MEV três soluções irrigadoras finais endodônticas para verificar qual ...
Resende, Gimol Benchimol de
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Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Understanding the Dynamics of Inflammatory Cytokines in Endodontic Diagnosis: A Systematic Review
DiagnosticsThe primary aim of this literature review is to delineate the key inflammatory cytokines involved in the pathophysiology of pulp inflammation. By elucidating the roles of these cytokines, a deeper comprehension of the distinct stages of inflamed pulp can
Ignacio Barbero-Navarro +5 more
doaj +1 more source
Atividade antibiofilme da solução de nanopartículas de óxido de zinco [PDF]
, 2014 TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.O objetivo deste estudo foi avaliar a efetividade da solução de hipoclorito de sódio (NaOCl) 1%, digluconato de clorexidina (CHX) 2% e de nanopartículas de
Orsi, Morgana Thays
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Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source