Results 171 to 180 of about 3,495,020 (259)

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Canal Boat Along an Unidentified Canal 2

open access: yes
One black and white photographic print of a canal boat on an unidentified canal, probably the Ohio and Erie Canal in eastern Ohio or the Miami and Erie Canal in western Ohio.
Canal Society of Ohio
core  

Regulatory harmonization: Evolution, globalization and future directions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm   +2 more
wiley   +1 more source

Expert consensus on management of instrument separation in root canal therapy. [PDF]

open access: yesInt J Oral Sci
Fan Y   +35 more
europepmc   +1 more source

Canal Boat Along an Unidentified Canal 1

open access: yes
One black and white photographic print of a canal boat on an unidentified canal, probably the Ohio and Erie Canal in eastern Ohio or the Miami and Erie Canal in western Ohio.
Canal Society of Ohio
core  

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Unidentified Canal Boat on Canal 1

open access: yes
One black and white photographic print of an unidentified canal boat on a canal, probably the Ohio and Erie Canal in eastern Ohio or the Miami and Erie Canal in western Ohio.
Canal Society of Ohio
core  

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