Results 221 to 230 of about 143,099 (363)

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

open access: yesAdvanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang   +10 more
wiley   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen   +17 more
wiley   +1 more source

IN VIVO AND IN VITRO EFFECTIVENESS OF ROTARY NICKEL‐TITANIUM VS MANUAL STAINLESS STEEL INSTRUMENTS FOR ROOT CANAL THERAPY: SYSTEMATIC REVIEW AND META‐ANALYSIS

open access: yesJournal of Evidence-Based Dental Practice, 2017
M. Del Fabbro   +5 more
semanticscholar   +1 more source

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