Results 221 to 230 of about 171,329 (359)

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Exploring dentists' experiences of endodontic file fracture during root canal treatment: a phenomenological study. [PDF]

BMC Oral Health
Khosravi MR, Banafshi Z, Ebrahimi R, Jalali R.   +3 more
europepmc   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Innovative 3D-printed dental teaching model for root canal treatment simulation. [PDF]

J Dent Sci
Chen SY, Wu YC, Wu JR, Lin CY, Hung YJ, Huang TW, Shieh YS.   +6 more
europepmc   +1 more source

Microbial Ecosystem Analysis in Root Canal Infections Refractory to Endodontic Treatment

, 2020
Luiz Carlos Feitosa Henriques, Luciana Brito, Warley Luciano Faria Tavares, Ricardo Teles, Leda Quércia Vieira, Flávia Rodrigues Teles, Antônio Paulino Ribeiro Sobrinho   +6 more
openalex   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Additional file 1 of Postoperative pain following root canal treatment with XP-Endo Finisher–assisted irrigant activation: a double-blind randomized controlled trial

Rai, Namith, Narkedamalli, Raj Kumar, Ballal, Nidambur Vasudev   +2 more
openalex   +1 more source

Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics

Advanced Science, EarlyView.
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran, Nil Kanatha Pandey, David P. Cormode, Daeyeon Lee, Edward Steager, Hyun Koo   +5 more
wiley   +1 more source

Effect of Different Irrigation Activation Techniques on Smear Layer Removal in Root Canal Treatment.

J Pharm Bioallied Sci
Panda B, Panda S, Hota S, Dass D, Arya A, Marwaha J.   +5 more
europepmc   +1 more source

Anxiety among patients with single versus multiple visits for root canal treatment. [PDF]

Bioinformation
G S, Mathew J, Madhavan R, J S AN, Dubey S, Sahoo U.   +5 more
europepmc   +1 more source