Results 161 to 170 of about 407,625 (291)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Root cause analysis of the challenges to sustain effectiveness of clinical pharmacist-driven antimicrobial stewardship in a Chinese Tertiary Hospital. [PDF]

Front Public Health
Zhao Z, Zhou Y, Li C, Xu J, Xu C, Lu H, Gao Y, Yu B, Shi G, Zhao Y, Li Z, Yang F, Ding P.   +12 more
europepmc   +1 more source

What are the experiences of team members involved in root cause analysis? A qualitative study. [PDF]

BMC Health Serv Res, 2023
Willis R, Jones T, Hoiles J, Hibbert PD, Schultz TJ.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The associated factors of root cause analysis of incident reporting in public primary healthcare in Malaysia. [PDF]

Sci Rep
Rani HA, Ismail A, Rahman HIA, Sani NARM.   +3 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Root cause analysis to identify physical causes

, 2012
International audienceThis paper proposes a methodology to develop a root cause analysis (RCA) tool which purpose is to identify the physical bad actors that cause performances deviations of an industrial system. This model is based on the integration of
Iung, Benoît, Medina-Oliva, Gabriela, Ruin, Thomas, Barberá, Luis, Viveros, Pablo   +4 more
core  

Cloned Journals: Root Cause Analysis and Way Forward

Journal of Marine Medical Society
Krishnan Shanmuganandan
doaj   +1 more source

Improved bayesian network with graph attention and prior algorithm for aircraft engine fault root cause analysis. [PDF]

Sci Rep
Yuan L, Han G, Dong P.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source