Results 231 to 240 of about 1,671,483 (282)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers
FEBS Open Bio, EarlyView.Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo +4 more
wiley +1 more source
The effect of family-centered care on unplanned emergency room visits, hospital readmissions and intensive care admissions after surgery: a root cause analysis from a prospective multicenter study in the Netherlands. [PDF]
Patient Saf SurgKreca SM +6 more
europepmc +1 more source
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EDFA Technical Articles, 2020
Abstract A root-cause analysis is used to identify the initiating, or root, of a causal chain that leads to an observed undesirable outcome. It is useful in helping managers to focus their problem-solving efforts on providing remedies to issues that actually prevent the undesirable outcome from recurring.
Greg Fisher +2 more
openaire +2 more sources
Abstract A root-cause analysis is used to identify the initiating, or root, of a causal chain that leads to an observed undesirable outcome. It is useful in helping managers to focus their problem-solving efforts on providing remedies to issues that actually prevent the undesirable outcome from recurring.
Greg Fisher +2 more
openaire +2 more sources
2023
Abstract Root cause analysis (RCA) is a tool intended to analyze the roots of a problem in a structured and meticulous manner so that the underlying cause, contributing factors, or system vulnerabilities of an incident are identified and addressed in an effort to prevent future adverse events.
Luis Tueme, Nawal E. Ragheb-Mueller
openaire +1 more source
Abstract Root cause analysis (RCA) is a tool intended to analyze the roots of a problem in a structured and meticulous manner so that the underlying cause, contributing factors, or system vulnerabilities of an incident are identified and addressed in an effort to prevent future adverse events.
Luis Tueme, Nawal E. Ragheb-Mueller
openaire +1 more source
2015
Root cause analysis (RCA) is a retrospective method of analyzing sentinel events and errors aimed at identification of the “root cause” of the problem. The RCA process should be initiated upon identification of a sentinel event, and typically includes the formation of a team of key stakeholders, investigation of the situation and collection of data on ...
openaire +2 more sources
Root cause analysis (RCA) is a retrospective method of analyzing sentinel events and errors aimed at identification of the “root cause” of the problem. The RCA process should be initiated upon identification of a sentinel event, and typically includes the formation of a team of key stakeholders, investigation of the situation and collection of data on ...
openaire +2 more sources