Results 141 to 150 of about 6,155,597 (302)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Unit Root Tests With Markov-Switching [PDF]
Diba and Grossman (1988) and Hamilton and Whiteman (1985) recommended unit root tests for rational bubbles. They argued that if stock prices are not more explosive than dividends, then it can be concluded that rational bubbles are not present.
Gee Kwang Randolph Tan, Xiao Qin
core +2 more sources
AgronomyThe transplanted cotton–wheat rotation enables dual cropping but alters root system architecture, typically suppressing taproot growth and promoting shallow lateral and fibrous roots, with unclear implications for irrigation response and water use ...
Xuan Guo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Threshold autoregression with a near unit root [PDF]
unit root;autoregressive ...
Hansen,B.E., Caner,M.
core
Seasonal root growth and dry matter partitioning in perennial wheat
Plant Production SciencePerennial wheats produced grain for up to 4 years in southern Australia, but quantitative data are lacking on dry matter (DM) allocation above- and below-ground over regrowth cycles.
Jesmin Aktar +3 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Regional convergence across European Union [PDF]
This paper analyzes the per-capita incomes convergence process across 140 NUTS2 European regions during the period 1980-1999. Two methods of analysis have been used.
Cristina Brasili, Luciano Gutierrez
core
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source