Results 131 to 140 of about 591,997 (315)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Gibberellin biosynthesis and signalling in Arabidopsis root growth [PDF]

, 2011
Using targeted expression of a constitutively active repressor of GA signalling Susana Ubeda-Tomas et al., (2007) demonstrated that GA action in endodermal cells is necessary for correct root growth.
Barker, Richard, Barker, R.
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Synergistic Effects of Crop Aboveground Growth and Root Traits Guarantee Stable Yield of Strip Relay Intercropping Maize

Agronomy
In order to reveal the yield-increasing mechanism of relay intercropping (RI) maize with different varieties from the perspective of plant growth, source sink relationship, and root growth, a two-factor randomized block design trial was designed, which ...
Liang Feng, Yun Hu, Kai Shi, Haiying Tang, Tian Pu, Xiaochun Wang, Wenyu Yang   +6 more
doaj   +1 more source

The effectiveness of ectomycorrhizal fungi in increasing the growth of Eucalyptus globulus Labill. in relation to root colonization and hyphal development in soil

, 1994
Forty-seven different isolates of ectomycorrhizal fungi, from the different genera, were screened for their effectiveness in increasing the growth of Eucalyptus globulin La hi 11. where supply of P is deficient.
Grove, T.S., Thomson, B.D., Malajczuk, N., Hardy, G.E.St.J.   +3 more
core  

Role of auxins, polyamines and ethylene in root formation and growth in sweet orange

, 2011
The primary objective of this work was to investigate the role of polyamines (PAs) on root formation and growth in two sweet orange (Citrus sinensis L. Osb.) cultivars Pineapple and Pêra. Adventitious shoots (30-d-old) derived from epicotyl explants were
A. F. S. Mendes, W. S. Soares-Filho, W. C. Otoni, M. G. C. Costa, L. C. Cidade   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Repeatable Imaging of Soil Processes Through a Stabilized Port: Examples of (i) Soil Contaminants and (ii) Plant Root Growth

Sensors
This work presents an imaging testing system (software and hardware) that can generate repeatable images through a stabilized port in the soil for processes known to change with time.
Julio A. Zimbron, Christian C. Rayo
doaj   +1 more source

Triple superphosphate placement affects early growth of chickpea

, 2010
Fertilizer placement with and close to the seed may have inhibitory effects on early growth of plants. In a pot study, chickpea (Cicer arietinum L.) root growth and nodulation was assessed by placing triple superphosphate (TSP) with seed (0) and 2 or 5 ...
Bell, R.W., Johansen, C., Kabir, E.
core