Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Gibberellin transport affects lateral root growth through HY5 in response to far-red light. [PDF]
van Gelderen K +8 more
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Cytosolic Ca 2+ as a universal signal for rapid root growth regulation
Randuch M +5 more
europepmc +1 more source
MicroRNA319-TCP19-IAA3.2 Module Mediates Lateral Root Growth in <i>Populus tomentosa</i>. [PDF]
Li J +8 more
europepmc +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
The <i>RALF1-eIF4E1</i> Signaling Axis Mediates Root Hair Elongation, Flowering Time, and Stress Tolerance During Seed Germination and Early Root Growth in <i>Arabidopsis thaliana</i>. [PDF]
Zeng F +5 more
europepmc +1 more source
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
Winter wheat phenotyping for deep root growth and function, reduced water stress and increased uptake of deep N and water. [PDF]
Odone A +2 more
europepmc +1 more source
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source

