Results 101 to 110 of about 2,084,932 (380)
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Impact of small sample sizes on the internal quality control: statistical uncertainties in the determination of root mean square deviations with respect to the sample mean (RMSD) or to a target value (RMSTD) [PDF]
Christian Beier
openalex +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
A root-mean-square pressure fluctuations model for internal flow applications [PDF]
A transport equation for the root-mean-square pressure fluctuations of turbulent flow is derived from the time-dependent momentum equation for incompressible flow.
Chen, Y. S.
core +1 more source
The geometric mean of two matrices from a computational viewpoint [PDF]
The geometric mean of two matrices is considered and analyzed from a computational viewpoint. Some useful theoretical properties are derived and an analysis of the conditioning is performed.
Iannazzo, Bruno
core
Statistical properties of supersonic turbulence in the Lagrangian and Eulerian frameworks
We present a systematic study of the influence of different forcing types on the statistical properties of supersonic, isothermal turbulence in both the Lagrangian and Eulerian frameworks.
Federrath, Christoph +3 more
core +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
The Effect of Root-Mean-Square and Loudness-Based Calibration Approach on the Acceptable Noise Level
Background and Aim: Hearing and speech perception are essential in social life. As our environment contains many background noises in everyday conversations, it is necessary to evaluate the noise tolerance.
Raha Nekoutabar +2 more
doaj +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Measurement Model and Precision Analysis of Accelerometers for Maglev Vibration Isolation Platforms
High precision measurement of acceleration levels is required to allow active control for vibration isolation platforms. It is necessary to propose an accelerometer configuration measurement model that yields such a high measuring precision.
Qianqian Wu +6 more
doaj +1 more source

