Results 101 to 110 of about 71,245 (348)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

External apical root resorption in orthodontically treated Class II malocclusions with 2-phase protocol (A 10-year Experience)

Erbil Dental Journal, 2019
Background and objectives: External apical root resorption is one of the proposed sequels of fixed orthodontic appliances used for the treatment of different types of malocclusions specially class II.
Omar Fawzi Chawshli
doaj  

Salivary inflammatory biomarkers during initial orthodontic tooth movement [PDF]

, 2016
BACKGROUND: Orthodontic tooth movement is a complex process involving a number of inflammatory and anabolic/catabolic pathways. Further, successful treatment depends on proper timing of orthodontic measures with regard to patient’s growth spurt ...
Serrenho, Ana
core   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

A review of the methods used to study biocompatibility of Portland cement-derived materials used in dentistry [PDF]

, 2006
Advanced restorative dentistry may necessitate the need for surgical intervention to the infected root apex. Once access to the root end is achieved, the root apex is resected and filled with a dental restorative material.
Camilleri, Josette
core  

Nitrogen uptake and internal recycling in Zostera marina exposed to oyster farming: eelgrass potential as a natural biofilter [PDF]

, 2016
Oyster farming in estuaries and coastal lagoons frequently overlaps with the distribution of seagrass meadows, yet there are few studies on how this aquaculture practice affects seagrass physiology.
A Alexandre, A Alexandre, A Buhmann, A Cabello-Pasini, A Neori, Ana Alexandre, BJ Dudley, BR Dumbauld, BW Touchette, BW Touchette, C Buzzelli, CA Simenstad, CD Cornelisen, CM Maier, DH Ward, DM Booth, E Wagner, ET Apostolaki, FT Short, G Lepoint, G Lepoint, H Iizumi, H Peterson, H Peterson, HF Vinther, HF Vinther, HM Tallis, I Olivé, J Forde, J Stapel, J Stapel, J Terrados, J Zertuche-González, JA Vonk, JC Zieman, JM Burkholder, JM Hernández-Ayón, JM Ruiz, JM Sandoval-Gil, Jose Sandoval-Gil, JR Kelly, JW Fourqurean, K-S Lee, KJ McGlathery, L Rubio, LK Korhonen, LM Rasmusson, LM Wisehart, M Alkhatib, M Poumian-Tapia, M Ribas-Ribas, M Yamamuro, MA Hemminga, MA Hemminga, MA Hemminga, MA Skinner, MF Pedersen, MF Pedersen, ML Kellogg, N Hasegawa, N Marbá, O Invers, O Invers, RA Everett, RD Evans, Rui Santos, S García-Esquivel, S Sharma, T Alcoverro, T Alcoverro, TB Coplen, TBH Reusch, TJ Hoellein, VF Camacho-Ibar, Víctor F. Camacho-Ibar   +74 more
core   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source

Impact of fixed appliance treatment on root resorption in root canal-treated teeth: a systematic review and meta-analysis

Acta Odontologica Scandinavica
Objective: The relationship between orthodontic treatment and root resorption in endodontically treated teeth remains controversial. This systematic review and meta-analysis aimed to evaluate the effects of fixed appliance treatment on root resorption ...
Yongfang Feng, Rong Wang, Yumin Zhou, Shengnan Zhan   +3 more
doaj   +1 more source

Adverse effects of orthodontic treatment: A clinical perspective

Saudi Dental Journal, 2011
Orthodontic treatment is associated with a number of adverse effects, such as root resorption, pain, pulpal changes, periodontal disease, and temporomandibular dysfunction (TMD). Orthodontists should be aware of these effects and associated risk factors.
Nabeel F. Talic
doaj   +1 more source