Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu+15 more
wiley +1 more source
Long-term follow-up of maxillary incisors with sever apical root resorption [PDF]
E Levander, Olle Malmgren
openalex +1 more source
A therapeutic strategy is proposed for periodontitis using extracellular vesicles derived from EPO‐stimulated macrophages (EPO‐EVs). This schema demonstrates how EPO‐EVs enhance the osteogenic activity of mBMSCs in an inflammatory environment by inhibiting EGFR.
Shuchen Liu+10 more
wiley +1 more source
Ultrasound imaging of cortical bone: cortex geometry and measurement of porosity based on wave speed for bone remodeling estimation [PDF]
Intracortical US imaging extends B-mode imaging into bone using a dedicated image reconstruction algorithm that corrects for refraction at the bone-soft tissue interfaces. It has shown promising results in a few healthy, predominantly young adults, providing anatomical images of the cortex (periosteal and endosteal surfaces) along with estimations of ...
arxiv
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source
An evaluation of root resorption occurring during orthodontic treatment
Ch. R. Rudolph
openalex +2 more sources
Immunolocalization of vacuolar‐type H+‐ATPase, cathepsin K, matrix metalloproteinase‐9, and receptor activator of NFkB ligand in odontoclasts during physiological root resorption of human deciduous teeth [PDF]
Takahiro Oshiro+3 more
openalex +1 more source
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang+9 more
wiley +1 more source
Immunopathological response in external dental resorption [PDF]
The study of root resorption and its immunopathogenesis is extremely important for preserving teeth within the oral cavity. Resorption may be infl ammatory or by substitution and it can be triggered by traumatism, induced movement of teeth, periapical ...
Borba, Paulo Oliva de+2 more
core +1 more source
Radiographic diagnosis of root resorption in relation to orthodontics [PDF]
HELEN LEACH+2 more
openalex +1 more source