Results 71 to 80 of about 100,657 (258)
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Root Water Uptake as Simulated by Three Soil Water Flow Models
Vadose Zone Journal, 2012 We compared four root water uptake (RWU) models of different complexity that are all embedded in greater soil water flow models. The soil models used were SWAP (one-dimensional), FUSSIM2 (two-dimensional), and RSWMS (three-dimensional). Within SWAP, two RWU functions were utilized (SWAP-macro and SWAP-micro).
de Willigen, P. +3 more
openaire +2 more sources
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
A Continuous Root Water Uptake Isotope Mixing Model
Water Resources ResearchThe depth‐wise distribution of root water uptake is typically inferred through linear mixing models that utilize knowledge of stable water isotopes in soil and plants.
Han Fu +3 more
doaj +1 more source
Agricultural Water ManagementThe spatiotemporal pattern of root water uptake (RWU) depends on multiple factors, such as plant root biomass, soil water availability, and prevailing weather conditions at the site.
Anooja Thomas +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Journal of Integrative Agriculture, 2016 Crop root system plays an important role in the water cycle of the soil-plant-atmosphere continuum. In this study, combined isotope techniques, root length density and root cell activity analysis were used to investigate the root water uptake mechanisms ...
Fei GUO +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source