Results 141 to 150 of about 1,149,747 (305)
P(論文)Malformations of deciduous teeth occur is very rare, because of their primitive forms. The abnormality of the roots of deciduous teeth as well as of crowns is rare.
26351 +9 more
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Inicio sus estudios musicales, de piano y violín a muy temprana edad. Luego escogió definitivamente el piano, y estudió este instrumento y armonía, contrapunto y composición en Tartu (Dorpat).
Línea de Investigación en Musicología Histórica
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Groundwater plays a crucial role in supporting vegetation in hyper‐arid regions, yet its regulatory effects on deep‐rooted plants remain poorly understood. This study examined Alhagi sparsifolia Shap., a groundwater‐dependent desert shrub at the southern
Caibian Huang +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Cointegration and Unit Roots. [PDF]
This paper provides an updated survey of a burgeoning literature on testing, estimation and model specification in the presence of integrated variables.
Jenkinson, Tim +2 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

