Results 171 to 180 of about 1,015,736 (307)

Adjustment of Root System Architecture and Root Function in Response to Multifactorial Abiotic Stress. [PDF]

Physiol Plant
Dietz KJ.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Establishment of hairy root cultures of Lactuca serriola and enhancement of phenolic metabolites through methyl jasmonate elicitation. [PDF]

PLoS One
Asheri M, Farokhzad A, Naghavi M, Ghasemzadeh R, Azadi P, Zargar M.   +5 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Light modulates organ-specific gibberellin-abscisic acid crosstalk during drought response in Arabidopsis thaliana. [PDF]

Planta
Miksteinová T, Szecówka M, Petřík I, Urbanová T, Trávníčková T, Špundová M, Fellner M, Hedden P.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Root biomass fraction of forest-planted sugar maple seedlings varies with climate of population origin across a latitudinal gradient. [PDF]

Oecologia
Putnam RC, Reich PB.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Historical roots of extremist narratives in Europe

Bauvois is co-athor and co-oordinator of the Gender section of this report on the Historical Roots of Extremist Narratives. This report delves into the historical roots and evolution of extremist narratives in Europe, spanning from the late 19th century ...
Bauvois, Gwenaëlle
core  

Root endophytic Aquapteridospora rhizicola enhances growth and heavy metal tolerance of Miscanthus sinensis Andersson at a sedimentary site via indole-3-acetic acid and melanin production enhanced by high Fe and high temperature. [PDF]

PLoS One
Matsushiro Y, Doyama K, Haruma T, Lu X, Masuya H, Shingai K, Tomiyama S, Isoda H, Yamaji K.   +8 more
europepmc   +1 more source