Results 91 to 100 of about 3,050,600 (310)

Harnessing the cognitive surplus of the nation: new opportunities for libraries in a time of change. The 2012 Jean Arnot Memorial Fellowship Essay. [PDF]

open access: yes, 2012
This essay is the winner of the 2012 Jean Arnot Memorial Fellowship. The essay draws on Rose Holley's experience of managing innovative library services that engage crowds such as The Australian Newspapers Digitisation Program and Trove, and her ongoing ...
Holley, Rose
core  

Duality and semi-group property for backward parabolic Ito equations

open access: yes, 2010
We study existence, uniqueness, semi-group property, and a priori estimates for solutions for backward parabolic Ito equations in domains with boundary. We study also duality between forward and backward equations.
Dokuchaev, Nikolai
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Rosa chinensis cv. Viridiflora phyllody phenotype is associated with misexpression of flower organ identity genes

open access: yesFrontiers in Plant Science, 2016
Phyllody is a flower abnormality in which leaf-like structures replace flower organs in all whorls. Here we investigated the origin and the molecular mechanism of phyllody phenotype in Rosa chinensis cv.
Huijun Yan   +11 more
doaj   +1 more source

A rose is a rose is a rose, or not [PDF]

open access: yesBlood, 2019
In this issue of Blood, Roubinian et al provide important evidence to confirm, and refute, a long-standing maxim in clinical medicine that a 1-unit transfusion of red blood cells (RBCs) should yield a posttransfusion hemoglobin increment of 1 g/dL. Although true, in general, this rule was not always accurate, and deviations could be misleading.
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Overview of the Scottish labour market [November 2008] [PDF]

open access: yes, 2008
Comparable figures on the labour market1 between Scotland and the United Kingdom in the second quarter of 2008 are summarised in Table 1. Labour Force Survey (LFS) data show that in the second three months of 2008 the level of employment in Scotland rose
Allan, Grant
core   +1 more source

Introduction to Gromov-Witten Theory

open access: yes, 2014
The goal of these notes is to provide an informal introduction to Gromov-Witten theory with an emphasis on its role in counting curves in surfaces. These notes are based on a talk given at the Fields Institute during a week-long conference aimed at ...
Rose, Simon
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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