Results 31 to 40 of about 493,317 (266)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Podocyturia an emerging biomarker for kidney injury

BMC Nephrology
Podocyte injury is an established hallmark of kidney disease progression. Podocyte loss is a widely proven hypothesis to explain, in part, glomerular damage.
Charbel Hanna, Hady El Etry, Maroun Ibrahim, Lynn Khalife, Sola Aoun Bahous, Wissam H. Faour   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Unveiling the unseen toll: exploring the impact of the Lebanese economic crisis on the health-seeking behaviors in a sample of patients with diabetes and hypertension

BMC Public Health
Background Against the backdrop of Lebanon’s escalating multifaceted crisis which resulted in medication shortages for chronic diseases and unaffordable healthcare services, the current study endeavors to shed light on a critical yet overlooked facet of ...
Michelle Cherfane, Myriam Boueri, Elio Issa, Racha Abdallah, Ali Hamam, Kassem Sbeity, Anthony Saad, Aniella Abi-Gerges   +7 more
doaj   +1 more source

Bitstream Evolution: An Open-Source FPGA Intrinsic Evolvable Hardware Toolkit

IEEE Access
The field of intrinsic, bitstream-level, evolvable hardware has recently been resurrected and interest in the area has begun to grow. This paper presents a low barrier-to-entry software and hardware platform allowing evolvable hardware researchers to ...
Allyn Loyd, Daniel Gaull, Logan Manthey, Nicklas Carpenter, Derek Whitley, Jason A. Yoder   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Exploring gender disparity in medicine: perceptions of female physicians in Lebanon

BMC Medical Education
Background Global research on gender bias has highlighted key trends in discrimination and inequality across various fields, including medicine. In Lebanon, a nation celebrated for its diverse cultural landscape and increasing female representation in ...
Sibelle Kassouf, Elma Nassar, Hassan Cherri, Shaza Mortada, Kamar Eid, Leen Khalife, Aimee Daccache, Aniella Abi-Gerges   +7 more
doaj   +1 more source

South and Central America Cut Flower Production and Postharvest Survey

HortTechnology, 2019
Imports of cut flowers into the United States have doubled in the last 20 years and come mainly from Colombia and Ecuador. We surveyed the cut flower industry in South and Central America, focusing on Colombia and Ecuador, to determine their production ...
Cristian E. Loyola , John M. Dole, Rebecca Dunning   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source